Ald-Ph-PEG2-amine
- Product Name
- Ald-Ph-PEG2-amine
- CAS No.
- 2055013-56-2
- Chemical Name
- Ald-Ph-PEG2-amine
- Synonyms
- Ald-Ph-PEG2-amine;CHO-Ph-PEG2-amine TFA;CHO-Ph-CONH-PEG2-amine;Ald-Ph-amido-C2-PEG2-amine;Ald-Ph-PEG2-amine TFA salt;CHO-Ph-CONH-PEG2-amine TFA;Benzamide, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-4-formyl-
- CBNumber
- CB23363843
- Molecular Formula
- C14H20N2O4
- Formula Weight
- 280.32
- MOL File
- 2055013-56-2.mol
Ald-Ph-PEG2-amine Property
- Boiling point:
- 507.8±45.0 °C(Predicted)
- Density
- 1.166±0.06 g/cm3(Predicted)
- pka
- 13.53±0.46(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Ald-Ph-PEG2-amine Chemical Properties,Usage,Production
Description
Ald-Ph-PEG2-amine TFA salt is a small molecule PEG linker with a benzaldehyde moiety and a terminal amine NH2 group. The benzaldehyde can undergo reactions with primary amine groups. The primary amine can react with carboxylic acids, activated NHS esters and other carbonyl compounds. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous solutions.
Uses
Ald-Ph-amido-C2-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Ald-Ph-PEG2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ald-Ph-PEG2-amine manufacturers
- Product
- CHO-Ph-CONH-PEG2-amine 2055013-56-2
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-23