ChemicalBook > CAS DataBase List > Acid-PEG3-mono-methyl ester

Acid-PEG3-mono-methyl ester

Product Name: Acid-PEG3-mono-methyl ester
CAS No.: 1807505-26-5
Chemical Name: Acid-PEG3-mono-methyl ester
Synonyms: COOH-PEG3-COOMe;CAS_1807505-26-5;COOH-PEG3-CH2CH2COOMe;Acid-PEG3-mono-methyl ester;MeOOCCH2CH2O-PEG2-CH2CH2COOH;CARBOXY-PEG3-MONO-METHYL ESTER;4,7,10,14-Tetraoxapentadecanoic acid, 13-oxo-;3-Oxo-2,6,9,12-tetraoxapentadecan-15-oic Acid;MeOOCCH2CH2O-PEG2-CH2CH2COOH/4,7,10,14-Tetraoxapentadecanoic acid, 13-oxo-
CBNumber: CB13062291
Molecular Formula: C11H20O7
Formula Weight: 264.27
MOL File: 1807505-26-5.mol

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Acid-PEG3-mono-methyl ester Property

Boiling point:: 396.7±32.0 °C(Predicted)
Density: 1.162±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Liquid
pka: 4.27±0.10(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS108037
Product name: Carboxy-PEG3-mono-Methylester
Purity: 94%
Packaging: 250mg
Price: $531
Updated: 2021/12/16

BroadPharm

Product number: BP-22142
Product name: Acid-PEG3-mono-methylester
Purity: 92%
Packaging: 250mg
Price: $540
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1358
Product name: Carboxy-PEG3-mono-methyl ester
Packaging: 250mg
Price: $623
Updated: 2021/12/16

BroadPharm

Product number: BP-22142
Product name: Acid-PEG3-mono-methylester
Purity: 92%
Packaging: 500mg
Price: $850
Updated: 2021/12/16

BroadPharm

Product number: BP-22142
Product name: Acid-PEG3-mono-methylester
Purity: 92%
Packaging: 1g
Price: $1250
Updated: 2021/12/16

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Acid-PEG3-mono-methyl ester Chemical Properties,Usage,Production

Description

Acid-PEG3-mono-methyl ester is a PEG linker with a carboxylic acid and methyl ester group. Methyl ester can be hydrolyzed under strong basic condition. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

Acid-PEG3-mono-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Acid-PEG3-mono-methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Acid-PEG3-mono-methyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: COOH-PEG3-COOMe 1807505-26-5
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

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Acid-PEG3-mono-methyl ester

CARBOXY-PEG3-MONO-METHYL ESTER

CAS_1807505-26-5

COOH-PEG3-COOMe

4,7,10,14-Tetraoxapentadecanoic acid, 13-oxo-

MeOOCCH2CH2O-PEG2-CH2CH2COOH

MeOOCCH2CH2O-PEG2-CH2CH2COOH/4,7,10,14-Tetraoxapentadecanoic acid, 13-oxo-

3-Oxo-2,6,9,12-tetraoxapentadecan-15-oic Acid

COOH-PEG3-CH2CH2COOMe

1807505-26-5