Acid-PEG4-mono-methyl ester
- Product Name
- Acid-PEG4-mono-methyl ester
- CAS No.
- 2028284-75-3
- Chemical Name
- Acid-PEG4-mono-methyl ester
- Synonyms
- COOH-PEG4-COOMe;CAS_2028284-75-3;Acid-PEG4-Methyl Ester;acid-PEG3-methyl ester;Acid-PEG4-mono-methyl ester;MeOOCCH2CH2O-PEG3-CH2CH2COOH;3-Oxo-2,6,9,12,15-pentaoxaoctadecan-18-oic acid;4,7,10,13-Tetraoxahexadecanedioic acid, 1-methyl ester;3-[2-[2-[2-(3-methoxy-3-oxo-propoxy)ethoxy]ethoxy]ethoxy]propanoic acid;3-[2-[2-[2-(3-methoxy-3-oxo-propoxy)ethoxy]ethoxy]ethoxy]propanoic acid - [M84526]
- CBNumber
- CB73162823
- Molecular Formula
- C13H24O8
- Formula Weight
- 308.32486
- MOL File
- 2028284-75-3.mol
Acid-PEG4-mono-methyl ester Property
- Boiling point:
- 433.8±40.0 °C(Predicted)
- Density
- 1.156±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 4.28±0.10(Predicted)
- form
- Liquid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- AS108089
- Product name
- Acid-PEG4-mono-Methylester
- Purity
- 94%
- Packaging
- 250mg
- Price
- $531
- Updated
- 2021/12/16
- Product number
- BP-23330
- Product name
- Acid-PEG4-mono-methylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- BP-23330
- Product name
- Acid-PEG4-mono-methylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $850
- Updated
- 2021/12/16
- Product number
- BP-23330
- Product name
- Acid-PEG4-mono-methylester
- Purity
- 98%
- Packaging
- 1g
- Price
- $1250
- Updated
- 2021/12/16
- Product number
- AS016794
- Product name
- 3-Oxo-2,6,9,12,15-pentaoxaoctadecan-18-oicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $1789
- Updated
- 2021/12/16
Acid-PEG4-mono-methyl ester Chemical Properties,Usage,Production
Description
Acid-PEG4-mono-methyl ester is a PEG linker with a carboxylic acid and methyl ester group. Methyl ester can be hydrolyzed under strong basic condition. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
Acid-PEG4-mono-methyl ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23. DOI:10.1016/j.jconrel.2016.02.017
Acid-PEG4-mono-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Acid-PEG4-mono-methyl ester Suppliers
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View Lastest Price from Acid-PEG4-mono-methyl ester manufacturers
- Product
- Acid-PEG4-mono-methyl ester 2028284-75-3
- Price
- US $1.80/KG
- Min. Order
- 1g
- Purity
- 96%-99%
- Supply Ability
- 1kg/10kg/100kg
- Release date
- 2020-11-11
- Product
- COOH-PEG4-COOMe 2028284-75-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23