S-acetyl-PEG3-acid
- Product Name
- S-acetyl-PEG3-acid
- CAS No.
- 1421933-33-6
- Chemical Name
- S-acetyl-PEG3-acid
- Synonyms
- CAS_1421933-33-6;S-acetyl-PEG-COOH;S-acetyl-PEG3-acid;S-acetyl-PEG3-COOH;S-Acetyl-PEG3-C2-acid;Acid-PEG3-S-methyl ethanethioate;14-Oxo-4,7,10-trioxa-13-thiapentadecanoic acid;2-oxo-6,9,12-trioxa-3-thiapentadecan-15-oic acid;4,7,10-Trioxa-13-thiapentadecanoic acid, 14-oxo-;3-((2-(2-(acetylthio)ethoxy)ethoxy)ethoxy)propanoic acid
- CBNumber
- CB03062643
- Molecular Formula
- C11H20O6S
- Formula Weight
- 280.34
- MOL File
- 1421933-33-6.mol
S-acetyl-PEG3-acid Property
- Boiling point:
- 421.4±40.0 °C(Predicted)
- Density
- 1.193±0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 4.28±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P999885
- Product name
- S-acetyl-PEG3-acid
- Packaging
- 10mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- P999885
- Product name
- S-acetyl-PEG3-acid
- Packaging
- 50mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- BP-20948
- Product name
- S-acetyl-PEG3-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BIPG1757
- Product name
- S-acetyl-PEG3-acid
- Packaging
- 250mg
- Price
- $740
- Updated
- 2021/12/16
- Product number
- POL0002533
- Product name
- S-ACETYL-PEG3-ACID
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $997.5
- Updated
- 2021/12/16
S-acetyl-PEG3-acid Chemical Properties,Usage,Production
Description
S-acetyl-PEG3-acid is a PEG linker containing a sulfur acetyl group and a terminal carboxylic acid. The sulfur acetyl group can be deprotected to produce a thiol moiety. The terminal carboxylic acid can react with primary amines in the presence of EDC or HATU to produce amide bonds. The hydrophilic PEG linker increase the water solubility of the compound in aqueous media.
Uses
S-Acetyl-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
S-acetyl-PEG3-acid Preparation Products And Raw materials
Raw materials
Preparation Products
S-acetyl-PEG3-acid Suppliers
- Tel
- 400-8592883
- Fax
- 0731-82251112
- sales@huatengsci.com
- Country
- China
- ProdList
- 5873
- Advantage
- 58
- Tel
- 027-65563561
- Fax
- 86-27-59218822
- sales@borenpharm.com
- Country
- China
- ProdList
- 1245
- Advantage
- 55
- Tel
- Fax
- -
- 13006575422@163.com
- Country
- China
- ProdList
- 6355
- Advantage
- 58
- Tel
- 0371-0371-55629727 13323845623
- Fax
- 037155629727
- 2885676761@qq.com
- Country
- China
- ProdList
- 10029
- Advantage
- 58
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28772
- Advantage
- 58
- Tel
- 021-61469567 13482353728
- Fax
- 021-61161605
- sales@fdc-chemical.com
- Country
- China
- ProdList
- 9964
- Advantage
- 58
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
- Tel
- 0371-55051623 18137891487
- Fax
- QQ:2853979817
- 3983243027@qq.com
- Country
- China
- ProdList
- 9806
- Advantage
- 58
- Tel
- 0411-39042497
- Fax
- 0411-39042693
- sales@alphabiopharm.com
- Country
- China
- ProdList
- 1951
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32467
- Advantage
- 58
View Lastest Price from S-acetyl-PEG3-acid manufacturers
- Product
- AcS-PEG3-acid 1421933-33-6
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-25