S-acetyl-PEG4-t-butyl ester
- Product Name
- S-acetyl-PEG4-t-butyl ester
- CAS No.
- 1818294-26-6
- Chemical Name
- S-acetyl-PEG4-t-butyl ester
- Synonyms
- AcS-PEG4-COOtBu;S-acetyl-PEG4-Boc;S-acetyl-dPEG5-t-boc;S-acetyl-PEG4-t-butyl ester;tert-butyl 2-oxo-6,9,12,15-tetraoxa-3-thiaoctadecan-18-oate;4,7,10,13-Tetraoxa-16-thiaoctadecanoic acid, 17-oxo-, 1,1-dimethylethyl ester
- CBNumber
- CB53062648
- Molecular Formula
- C17H32O7S
- Formula Weight
- 380.5
- MOL File
- 1818294-26-6.mol
S-acetyl-PEG4-t-butyl ester Property
- form
- Liquid
- color
- Brown to reddish brown
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-20947
- Product name
- S-acetyl-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 1g
- Price
- $750
- Updated
- 2021/12/16
- Product number
- BIPG1768
- Product name
- S-acetyl-PEG4-t-butyl ester
- Packaging
- 500mg
- Price
- $759
- Updated
- 2021/12/16
S-acetyl-PEG4-t-butyl ester Chemical Properties,Usage,Production
Description
S-acetyl-PEG4-t-butyl ester is a PEG linker containing a sulfur acetyl group and a t-butyl ester. The sulfur acetyl group can be deprotected to form a thiol group. The t-butyl ester can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
Uses
S-acetyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
S-acetyl-PEG4-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from S-acetyl-PEG4-t-butyl ester manufacturers
- Product
- AcS-PEG4-COOtBu 1818294-26-6
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-06
- Product
- AcS-PEG4-t-butyl ester 1818294-26-6
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25