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S-acetyl-PEG4-Propargyl

Product Name
S-acetyl-PEG4-Propargyl
CAS No.
1422540-88-2
Chemical Name
S-acetyl-PEG4-Propargyl
Synonyms
Acs-PEG4-propargyl;Reaxys ID: 23366071;S-acetyl-PEG4-Alkyne;Acetylthio-PEG4-Alkyne;S-acetyl-PEG4-Propargyl;S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ethanethioate;Ethanethioic Acid S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ester
CBNumber
CB93163132
Molecular Formula
C13H22O5S
Formula Weight
290.38
MOL File
1422540-88-2.mol
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S-acetyl-PEG4-Propargyl Property

Boiling point:
375.6±37.0 °C(Predicted)
Density 
1.102±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in DMSO, DCM, DMF
form 
clear liquid
color 
Yellow to Amber to Dark red
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Safety

HS Code 
2923.90.0100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
T3698
Product name
Acetylthio-PEG4-Alkyne
Packaging
50MG
Price
$167
Updated
2026/03/19
TCI Chemical
Product number
T3698
Product name
Acetylthio-PEG4-Alkyne
Packaging
250MG
Price
$501
Updated
2026/03/19
BroadPharm
Product number
BP-23134
Product name
S-acetyl-PEG4-propargyl
Purity
98%
Packaging
500mg
Price
$660
Updated
2021/12/16
BroadPharm
Product number
BP-23134
Product name
S-acetyl-PEG4-propargyl
Purity
98%
Packaging
1g
Price
$990
Updated
2021/12/16
Chem-Impex
Product number
41705
Product name
Acetylthio-PEG4-alkyne,98%(GC)
Purity
98%(GC)
Packaging
250MG
Price
$1128.96
Updated
2021/12/16
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S-acetyl-PEG4-Propargyl Chemical Properties,Usage,Production

Description

S-acetyl-PEG4-propargyl is a PEG linker containing a sulfur acetyl group and a propargyl moiety. The sulfur acetyl group can be deprotected to produce a thiol compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of the compounds in the aqueous media.

Uses

S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

S-acetyl-PEG4-Propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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S-acetyl-PEG4-Propargyl Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
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80
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5873
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58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
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Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
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58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
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58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
13892832556
Email
2440688701@qq.com
Country
China
ProdList
1995
Advantage
58
Xiamen Sinopeg Biotech Co., Ltd.
Tel
400-9189898 17359873007
Email
sales@sinopeg.com
Country
China
ProdList
1000
Advantage
58
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View Lastest Price from S-acetyl-PEG4-Propargyl manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
Acs-PEG4-propargyl 1422540-88-2
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-03
Xian confluore Biological Technology Co., Ltd.
Product
Acs-PEG4-propargyl 1422540-88-2
Price
US $0.00/mg
Min. Order
500mg
Purity
>98.00%
Supply Ability
500mg
Release date
2024-03-25

1422540-88-2, S-acetyl-PEG4-PropargylRelated Search:


  • S-acetyl-PEG4-Propargyl
  • S-acetyl-PEG4-Alkyne
  • Reaxys ID: 23366071
  • Acetylthio-PEG4-Alkyne
  • Ethanethioic Acid S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ester
  • S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ethanethioate
  • Acs-PEG4-propargyl
  • 1422540-88-2
  • C13H22O5S
  • peg