S-acetyl-PEG4-Propargyl
- Product Name
- S-acetyl-PEG4-Propargyl
- CAS No.
- 1422540-88-2
- Chemical Name
- S-acetyl-PEG4-Propargyl
- Synonyms
- Acs-PEG4-propargyl;Reaxys ID: 23366071;S-acetyl-PEG4-Alkyne;Acetylthio-PEG4-Alkyne;S-acetyl-PEG4-Propargyl;S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ethanethioate;Ethanethioic Acid S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ester
- CBNumber
- CB93163132
- Molecular Formula
- C13H22O5S
- Formula Weight
- 290.38
- MOL File
- 1422540-88-2.mol
S-acetyl-PEG4-Propargyl Property
- Boiling point:
- 375.6±37.0 °C(Predicted)
- Density
- 1.102±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- clear liquid
- color
- Yellow to Amber to Dark red
Safety
- HS Code
- 2923.90.0100
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- T3698
- Product name
- Acetylthio-PEG4-Alkyne
- Packaging
- 50MG
- Price
- $167
- Updated
- 2026/03/19
- Product number
- T3698
- Product name
- Acetylthio-PEG4-Alkyne
- Packaging
- 250MG
- Price
- $501
- Updated
- 2026/03/19
- Product number
- BP-23134
- Product name
- S-acetyl-PEG4-propargyl
- Purity
- 98%
- Packaging
- 500mg
- Price
- $660
- Updated
- 2021/12/16
- Product number
- BP-23134
- Product name
- S-acetyl-PEG4-propargyl
- Purity
- 98%
- Packaging
- 1g
- Price
- $990
- Updated
- 2021/12/16
- Product number
- 41705
- Product name
- Acetylthio-PEG4-alkyne,98%(GC)
- Purity
- 98%(GC)
- Packaging
- 250MG
- Price
- $1128.96
- Updated
- 2021/12/16
S-acetyl-PEG4-Propargyl Chemical Properties,Usage,Production
Description
S-acetyl-PEG4-propargyl is a PEG linker containing a sulfur acetyl group and a propargyl moiety. The sulfur acetyl group can be deprotected to produce a thiol compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of the compounds in the aqueous media.
Uses
S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
S-acetyl-PEG4-Propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
S-acetyl-PEG4-Propargyl Suppliers
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View Lastest Price from S-acetyl-PEG4-Propargyl manufacturers
- Product
- Acs-PEG4-propargyl 1422540-88-2
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-03
- Product
- Acs-PEG4-propargyl 1422540-88-2
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-25