S-acetyl-PEG4-Propargyl

Product Name: S-acetyl-PEG4-Propargyl
CAS No.: 1422540-88-2
Chemical Name: S-acetyl-PEG4-Propargyl
Synonyms: Acs-PEG4-propargyl;Reaxys ID: 23366071;S-acetyl-PEG4-Alkyne;Acetylthio-PEG4-Alkyne;S-acetyl-PEG4-Propargyl;S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ethanethioate;Ethanethioic Acid S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ester
CBNumber: CB93163132
Molecular Formula: C13H22O5S
Formula Weight: 290.38
MOL File: 1422540-88-2.mol

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S-acetyl-PEG4-Propargyl Property

Boiling point:: 375.6±37.0 °C(Predicted)
Density: 1.102±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: clear liquid
color: Yellow to Amber to Dark red

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Safety

HS Code: 2923.90.0100

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: T3698
Product name: Acetylthio-PEG4-Alkyne
Packaging: 50MG
Price: $209
Updated: 2025/07/31

TCI Chemical

Product number: T3698
Product name: Acetylthio-PEG4-Alkyne
Packaging: 250MG
Price: $626
Updated: 2025/07/31

BroadPharm

Product number: BP-23134
Product name: S-acetyl-PEG4-propargyl
Purity: 98%
Packaging: 500mg
Price: $660
Updated: 2021/12/16

BroadPharm

Product number: BP-23134
Product name: S-acetyl-PEG4-propargyl
Purity: 98%
Packaging: 1g
Price: $990
Updated: 2021/12/16

Chem-Impex

Product number: 41705
Product name: Acetylthio-PEG4-alkyne,98%(GC)
Purity: 98%(GC)
Packaging: 250MG
Price: $1128.96
Updated: 2021/12/16

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S-acetyl-PEG4-Propargyl Chemical Properties,Usage,Production

Description

S-acetyl-PEG4-propargyl is a PEG linker containing a sulfur acetyl group and a propargyl moiety. The sulfur acetyl group can be deprotected to produce a thiol compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of the compounds in the aqueous media.

Uses

S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

S-acetyl-PEG4-Propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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S-acetyl-PEG4-Propargyl Suppliers

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View Lastest Price from S-acetyl-PEG4-Propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Acs-PEG4-propargyl 1422540-88-2
Price: US $0.00/mg
Min. Order: 500mg
Purity: >98.00%
Supply Ability: 500mg
Release date: 2024-03-25

1422540-88-2, S-acetyl-PEG4-PropargylRelated Search:

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S-acetyl-PEG4-Propargyl

S-acetyl-PEG4-Alkyne

Reaxys ID: 23366071

Acetylthio-PEG4-Alkyne

Ethanethioic Acid S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ester

S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ethanethioate

Acs-PEG4-propargyl

1422540-88-2

C13H22O5S

peg