Acid-PEG5-TEMPO
- Product Name
- Acid-PEG5-TEMPO
- CAS No.
- 2055040-79-2
- Chemical Name
- Acid-PEG5-TEMPO
- Synonyms
- Acid-PEG5-TEMPO
- CBNumber
- CB93162827
- Molecular Formula
- C23H44N2O9
- Formula Weight
- 492.60346
- MOL File
- 2055040-79-2.mol
N-Bromosuccinimide Price
- Product number
- BP-23157
- Product name
- Acid-PEG5-TEMPO
- Purity
- 95%
- Packaging
- 100mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-23157
- Product name
- Acid-PEG5-TEMPO
- Purity
- 95%
- Packaging
- 250mg
- Price
- $750
- Updated
- 2021/12/16
Acid-PEG5-TEMPO Chemical Properties,Usage,Production
Description
Acid-PEG5-TEMPO is a PEG linker with a terminal carboxylic acid and TEMPO moiety. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound. TEMPO is a stable radical with applications in chemistry and biochemistry. It is used as a radical marker, a structural probe for biological systems in conjunction with electron spin resonance spectroscopy, a reagent in organic synthesis, and as a mediator in controlled radical polymerization. It is commonly used as a catalyst in organic chemistry synthesis for the oxidation of primary alcohols to aldehydes.
Uses
Acid-PEG5-TEMPO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Acid-PEG5-TEMPO Preparation Products And Raw materials
Raw materials
Preparation Products
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