Acid-PEG5-mono-methyl ester

Product Name: Acid-PEG5-mono-methyl ester
CAS No.: 1309460-30-7
Chemical Name: Acid-PEG5-mono-methyl ester
Synonyms: COOH-PEG5-COOMe;COOH-PEG5-CH2CH2COOMe;Acid-PEG5-Methyl Ester;Acid-PEG5-mono-methyl ester;MeOOCCH2CH2O-PEG4-CH2CH2COOH;3-oxo-2,6,9,12,15,18-hexaoxahenicosan-21-oic acid;4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-methyl ester
CBNumber: CB73062293
Molecular Formula: C15H28O9
Formula Weight: 352.38
MOL File: 1309460-30-7.mol

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Acid-PEG5-mono-methyl ester Property

Boiling point:: 469.4±45.0 °C(Predicted)
Density: 1.151±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DCM
pka: 4.28±0.10(Predicted)
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C15H28O9/c1-19-15(18)3-5-21-7-9-23-11-13-24-12-10-22-8-6-20-4-2-14(16)17/h2-13H2,1H3,(H,16,17)
InChIKey: LSGMOHWEFFVQEO-UHFFFAOYSA-N
SMILES: C(OC)(=O)CCOCCOCCOCCOCCOCCC(O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C183735
Product name: Carboxyl-PEG5-mono-methylEster
Packaging: 5mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-20440
Product name: Acid-PEG5-mono-methylester
Purity: 98%
Packaging: 250mg
Price: $540
Updated: 2021/12/16

BroadPharm

Product number: BP-20440
Product name: Acid-PEG5-mono-methylester
Purity: 98%
Packaging: 500mg
Price: $850
Updated: 2021/12/16

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Acid-PEG5-mono-methyl ester Chemical Properties,Usage,Production

Description

Acid-PEG5-mono-methyl ester is a PEG linker containing a terminal carboxylic acid and a mono-methyl ester functional group. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.

Uses

Acid-PEG5-mono-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Acid-PEG5-mono-methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Acid-PEG5-mono-methyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: COOH-PEG5-COOMe 1309460-30-7
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

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Acid-PEG5-mono-methyl ester

COOH-PEG5-COOMe

4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-methyl ester

Acid-PEG5-Methyl Ester

3-oxo-2,6,9,12,15,18-hexaoxahenicosan-21-oic acid

MeOOCCH2CH2O-PEG4-CH2CH2COOH

COOH-PEG5-CH2CH2COOMe

1309460-30-7

C15H28O9