ChemicalBook > CAS DataBase List > Propargyl-PEG9-amine

Propargyl-PEG9-amine

Product Name
Propargyl-PEG9-amine
CAS No.
2093153-98-9
Chemical Name
Propargyl-PEG9-amine
Synonyms
NH2-PEG9-Propargyl;Propargyl-PEG9-NH2;Propargyl-PEG9-amine;3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yn-1-amine;Propargyl-PEG9-NH2/3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yn-1-amine
CBNumber
CB93373764
Molecular Formula
C21H41NO9
Formula Weight
451.55
MOL File
2093153-98-9.mol
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Propargyl-PEG9-amine Property

Boiling point:
512.3±45.0 °C(Predicted)
Density 
1.075±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
pka
8.74±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23419
Product name
Propargyl-PEG9-amine
Purity
95%
Packaging
100mg
Price
$280
Updated
2021/12/16
Activate Scientific
Product number
AS104194
Product name
Propargyl-PEG9-NH2
Purity
95+%
Packaging
1g
Price
$721
Updated
2021/12/16
Acrotein
Product number
B-1147
Product name
Propargyl-PEG9-NH2
Purity
97%
Packaging
0.25g
Price
$265.84
Updated
2021/12/16
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Propargyl-PEG9-amine Chemical Properties,Usage,Production

Description

Propargyl-PEG9-amine has a propargyl group and an amine group. The amine group reacts with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) to form amide bonds. The propargyl group reacts with azides to form triazole linkage with the presence of copper as a catalyst.

Uses

Propargyl-PEG9-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG9-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1.

Propargyl-PEG9-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG9-amine Suppliers

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View Lastest Price from Propargyl-PEG9-amine manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG9-amine 2093153-98-9
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26

2093153-98-9, Propargyl-PEG9-amineRelated Search:


  • Propargyl-PEG9-amine
  • Propargyl-PEG9-NH2
  • Propargyl-PEG9-NH2/3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yn-1-amine
  • 3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yn-1-amine
  • NH2-PEG9-Propargyl
  • 2093153-98-9
  • C21H41NO9