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Propargyl-PEG6-NHS ester

Product Name
Propargyl-PEG6-NHS ester
CAS No.
2093153-99-0
Chemical Name
Propargyl-PEG6-NHS ester
Synonyms
Propargyl-PEG6-NHS;Propargyl-P5-NHS ester;Propargyl-PEG6-NHS ester;Propargyl-PEG5-CH2CH2COONHS;Propargyl-PEG5-C2-CONHS ester;Propynyl pentapolyethylene glycol succinimide acrylate;2,5-Dioxopyrrolidin-1-yl?4,7,10,13,16,19-hexaoxadocos-21-yn-1-oate;4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester;Propargyl-PEG5-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB33373762
Molecular Formula
C20H31NO10
Formula Weight
445.46
MOL File
2093153-99-0.mol
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Propargyl-PEG6-NHS ester Property

Boiling point:
530.8±60.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
solubility 
Soluble in DMSO, DCM
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS107820
Product name
Propargyl-PEG5-CH2CH2COONHS
Purity
97%
Packaging
250mg
Price
$437
Updated
2021/12/16
BroadPharm
Product number
BP-23422
Product name
Propargyl-PEG6-NHSester
Purity
98%
Packaging
1g
Price
$950
Updated
2021/12/16
Acrotein
Product number
B-1543
Product name
Propargyl-PEG5-CH2CH2COONHS
Purity
97%
Packaging
0.5g
Price
$440
Updated
2021/12/16
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Propargyl-PEG6-NHS ester Chemical Properties,Usage,Production

Description

Propargyl-PEG6-NHS ester is an amine reactive linker. The alkyne in this linker can react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reaction. The PEG spacer increases solubility of the molecule in aqueous media.

Uses

Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

Cleavable Linker; PEGs; Alkyl/ether

References

[1] Anandan Palani, et al. Insulin-incretin conjugates. WO2017160669A1.

Propargyl-PEG6-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG6-NHS ester Suppliers

T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80534353 19917294565
Email
et@chemextension.com
Country
China
ProdList
3828
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28772
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9964
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
Hangzhou Huarong Pharm Co., Ltd.
Tel
571-86758373 +8613588754946
Fax
0086-571-81131109
Email
sales@huarongpharm.com
Country
CHINA
ProdList
3148
Advantage
58
Wuhan Borenpharm Co., Ltd
Tel
027-65563561 18717150066
Fax
027-59218822
Email
3207347307@qq.com
Country
CHINA
ProdList
1238
Advantage
58
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View Lastest Price from Propargyl-PEG6-NHS ester manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
Propargyl-PEG6-NHS 2093153-99-0
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-03
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG6-NHS ester 2093153-99-0
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26

2093153-99-0, Propargyl-PEG6-NHS esterRelated Search:


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