Propargyl-PEG13-acid
- Product Name
- Propargyl-PEG13-acid
- CAS No.
- 1421676-62-1
- Chemical Name
- Propargyl-PEG13-acid
- Synonyms
- CAS_1421676-62-1;Propargyl-PEG14-PA;Propargyl-PEG13-PA;Propargyl-PEG-acid;Propargyl-PEG25-acid;Propargyl-PEG13-acid;Propargyl-PEG12-CH2CH2COOH;Poly(oxy-1,2-ethanediyl), α-(2-carboxyethyl)-ω-(2-propyn-1-yloxy)-
- CBNumber
- CB73134202
- Molecular Formula
- (C2H4O)nC6H8O3
- Formula Weight
- 0
- MOL File
- 1421676-62-1.mol
Propargyl-PEG13-acid Property
- solubility
- Soluble in Water, DMSO, DCM, DMF
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P839555
- Product name
- Propargyl-PEG14-acid
- Packaging
- 5mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- BP-22597
- Product name
- Propargyl-PEG13-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BP-22855
- Product name
- Propargyl-PEG14-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- BP-22998
- Product name
- Propargyl-PEG25-acid
- Purity
- 97%
- Packaging
- 50mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- BIPG1711
- Product name
- Propargyl-PEG13-acid
- Packaging
- 100mg
- Price
- $623
- Updated
- 2021/12/16
Propargyl-PEG13-acid Chemical Properties,Usage,Production
Description
Propargyl-PEG13-acid consists of an alkyne group and a carboxylic acid. The carboxylic acid reacts with amine groups to form amide bonds in the presence of EDC or HATU as an activator. The alkyne group is commonly used in copper catalyzed azide-alkyne Click Chemistry reactions. The hydrophilic PEG units enhance the solubility of the molecule in aqueous media.
Uses
Propargyl-PEG-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277
Propargyl-PEG13-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG13-acid Suppliers
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View Lastest Price from Propargyl-PEG13-acid manufacturers
- Product
- Propargyl-PEG14-PA 1421676-62-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-03
- Product
- Propargyl-PEG13-PA 1421676-62-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-03
- Product
- Propargyl-PEG12-CH2CH2COOH 1421676-62-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 500kg
- Release date
- 2026-01-29