ChemicalBook > CAS DataBase List > Propargyl-PEG13-acid

Propargyl-PEG13-acid

Product Name
Propargyl-PEG13-acid
CAS No.
1421676-62-1
Chemical Name
Propargyl-PEG13-acid
Synonyms
CAS_1421676-62-1;Propargyl-PEG-acid;Propargyl-PEG25-acid;Propargyl-PEG13-acid;Propargyl-PEG12-CH2CH2COOH;Poly(oxy-1,2-ethanediyl), α-(2-carboxyethyl)-ω-(2-propyn-1-yloxy)-
CBNumber
CB73134202
Molecular Formula
(C2H4O)nC6H8O3
Formula Weight
0
MOL File
1421676-62-1.mol
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Propargyl-PEG13-acid Property

solubility 
Soluble in Water, DMSO, DCM, DMF
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P839555
Product name
Propargyl-PEG14-acid
Packaging
5mg
Price
$65
Updated
2021/12/16
BroadPharm
Product number
BP-22597
Product name
Propargyl-PEG13-acid
Purity
98%
Packaging
100mg
Price
$320
Updated
2021/12/16
BroadPharm
Product number
BP-22855
Product name
Propargyl-PEG14-acid
Purity
98%
Packaging
100mg
Price
$350
Updated
2021/12/16
BroadPharm
Product number
BP-22998
Product name
Propargyl-PEG25-acid
Purity
97%
Packaging
50mg
Price
$450
Updated
2021/12/16
Apolloscientific
Product number
BIPG1711
Product name
Propargyl-PEG13-acid
Packaging
100mg
Price
$623
Updated
2021/12/16
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Propargyl-PEG13-acid Chemical Properties,Usage,Production

Description

Propargyl-PEG13-acid consists of an alkyne group and a carboxylic acid. The carboxylic acid reacts with amine groups to form amide bonds in the presence of EDC or HATU as an activator. The alkyne group is commonly used in copper catalyzed azide-alkyne Click Chemistry reactions. The hydrophilic PEG units enhance the solubility of the molecule in aqueous media.

Uses

Propargyl-PEG-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Propargyl-PEG13-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG13-acid Suppliers

Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
970
Advantage
59
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
3935
Advantage
55
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Adachibio Inc.
Tel
+81-8027837258; +8108027837258
Fax
0081-80278372055
Email
sales@adachibio.com
Country
Japan
ProdList
992
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
Wuhan Borenpharm Co., Ltd
Tel
027-65563561 18717150066
Fax
027-59218822
Email
3207347307@qq.com
Country
CHINA
ProdList
1238
Advantage
58
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View Lastest Price from Propargyl-PEG13-acid manufacturers

LAURENT
Product
Propargyl-PEG12-CH2CH2COOH 1421676-62-1
Price
US $2463.00/g
Min. Order
1g
Purity
98%
Supply Ability
500kg
Release date
2025-11-24
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG14-acid 1421676-62-1
Price
US $0.00/g
Min. Order
1g
Purity
>95.00%
Supply Ability
1g
Release date
2024-03-28
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG13-acid 1421676-62-1
Price
US $0.00/g
Min. Order
1g
Purity
>95.00%
Supply Ability
1g
Release date
2024-03-26