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Propargyl-PEG2-acid

Product Name
Propargyl-PEG2-acid
CAS No.
1859379-85-3
Chemical Name
Propargyl-PEG2-acid
Synonyms
Alkyne-PEG2-COOH;CAS_1859379-85-3;Propargyl-PEG1-COOH;Propargyl-PEG2-acid;Propargyl-PEG1-C2-COOH;Propyne-PEG1-CH2CH2COOH;3-[2-(2-Propyn-1-yloxy)ethoxy]propanoic acid;3-(2-(Prop-2-yn-1-yloxy)ethoxy)propanoic acid;Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-
CBNumber
CB03163104
Molecular Formula
C8H12O4
Formula Weight
172.18
MOL File
1859379-85-3.mol
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Propargyl-PEG2-acid Property

storage temp. 
-20°C
solubility 
DMSO: 250 mg/mL (1451.97 mM)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901566
Product name
Propargyl-PEG2-acid
Packaging
50MG
Price
$221
Updated
2023/06/20
BroadPharm
Product number
BP-23165
Product name
Propargyl-PEG2-acid
Purity
98%
Packaging
100mg
Price
$290
Updated
2021/12/16
ChemScene
Product number
CS-0068466
Product name
Propargyl-PEG2-acid
Purity
≥98.0%
Packaging
100mg
Price
$300
Updated
2021/12/16
Activate Scientific
Product number
AS104183
Product name
3-[2-(2-Propyn-1-yloxy)ethoxy]propanoic acid
Purity
95+%
Packaging
1g
Price
$439
Updated
2021/12/16
BroadPharm
Product number
BP-23165
Product name
Propargyl-PEG2-acid
Purity
98%
Packaging
250mg
Price
$450
Updated
2021/12/16
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Propargyl-PEG2-acid Chemical Properties,Usage,Production

Description

Propargyl-PEG2-acid is a linker consisting of propargyl and carboxylic acid functional groups. In the presence of activators (e.g. EDC, or HATU), the carboxylic acid reacts with primary amine to form a stable amide bond. The propargyl group reacts with azide group in biomolecules to yield a stable triazole linkage.

Uses

Propargyl-PEG2-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG2-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Propargyl-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG2-acid Suppliers

Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7189
Advantage
65
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
3987
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28812
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
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View Lastest Price from Propargyl-PEG2-acid manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG2-acid 1859379-85-3
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-26

1859379-85-3, Propargyl-PEG2-acidRelated Search:


  • Propargyl-PEG2-acid
  • Propyne-PEG1-CH2CH2COOH
  • 3-[2-(2-Propyn-1-yloxy)ethoxy]propanoic acid
  • Propargyl-PEG1-COOH
  • CAS_1859379-85-3
  • 3-(2-(Prop-2-yn-1-yloxy)ethoxy)propanoic acid
  • Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-
  • Propargyl-PEG1-C2-COOH
  • Alkyne-PEG2-COOH
  • 1859379-85-3