ChemicalBook > CAS DataBase List > Propargyl-PEG2-acid
Propargyl-PEG2-acid
- Product Name
- Propargyl-PEG2-acid
- CAS No.
- 1859379-85-3
- Chemical Name
- Propargyl-PEG2-acid
- Synonyms
- Alkyne-PEG2-COOH;CAS_1859379-85-3;Propargyl-PEG1-COOH;Propargyl-PEG2-acid;Propargyl-PEG1-C2-COOH;Propyne-PEG1-CH2CH2COOH;Propargyl-PEG1-CH2CH2COOH;Propargyl-PEG2-acid;3-[2-(2-Propyn-1-yloxy)ethoxy]propanoic acid;3-(2-(Prop-2-yn-1-yloxy)ethoxy)propanoic acid
- CBNumber
- CB03163104
- Molecular Formula
- C8H12O4
- Formula Weight
- 172.18
- MOL File
- 1859379-85-3.mol
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Propargyl-PEG2-acid Property
- storage temp.
- -20°C
- solubility
- DMSO: 250 mg/mL (1451.97 mM)
- form
- Liquid
- color
- Colorless to light yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 901566
- Product name
- Propargyl-PEG2-acid
- Packaging
- 50MG
- Price
- $165.9
- Updated
- 2025/07/31
BroadPharm
- Product number
- BP-23165
- Product name
- Propargyl-PEG2-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $290
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0068466
- Product name
- Propargyl-PEG2-acid
- Purity
- ≥98.0%
- Packaging
- 100mg
- Price
- $300
- Updated
- 2021/12/16
Activate Scientific
- Product number
- AS104183
- Product name
- 3-[2-(2-Propyn-1-yloxy)ethoxy]propanoic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $439
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-23165
- Product name
- Propargyl-PEG2-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $450
- Updated
- 2021/12/16
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Propargyl-PEG2-acid Chemical Properties,Usage,Production
Description
Propargyl-PEG2-acid is a linker consisting of propargyl and carboxylic acid functional groups. In the presence of activators (e.g. EDC, or HATU), the carboxylic acid reacts with primary amine to form a stable amide bond. The propargyl group reacts with azide group in biomolecules to yield a stable triazole linkage.
Uses
Propargyl-PEG2-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG2-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
reaction suitability
reaction type: click chemistry
reagent type: linker
IC 50
Non-cleavable Linker; PEGs
Propargyl-PEG2-acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Propargyl-PEG2-acid manufacturers
LAURENT
- Product
- Propargyl-PEG1-CH2CH2COOH 1859379-85-3
- Price
- US $70.67/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-19
Xian confluore Biological Technology Co., Ltd.
- Product
- Propargyl-PEG2-acid 1859379-85-3
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-26
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