Propargyl-PEG6-acid
- Product Name
- Propargyl-PEG6-acid
- CAS No.
- 1951438-84-8
- Chemical Name
- Propargyl-PEG6-acid
- Synonyms
- CAS_1951438-84-8;Propargyl-PEG6-acid;Propargyl-PEG5-C2-COOH;Propyne-PEG5-CH2CH2COOH;Propargyl-PEG5-CH2CH2COOH;Propargyl-PEG6-Propionic Acid;4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid;Propargyl-PEG5-CH2CH2COOH/4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid
- CBNumber
- CB23134212
- Molecular Formula
- C16H28O8
- Formula Weight
- 348.39
- MOL File
- 1951438-84-8.mol
Propargyl-PEG6-acid Property
- Boiling point:
- 462.8±45.0 °C(Predicted)
- Density
- 1.126±0.06 g/cm3(Predicted)
- refractive index
- n/D 1.469
- storage temp.
- -20°C
- solubility
- Soluble in Water
- form
- liquid
- pka
- 4.28±0.10(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 902667
- Product name
- Propargyl-PEG6-acid
- Packaging
- 250mg
- Price
- $482
- Updated
- 2024/03/01
- Product number
- 902667
- Product name
- Propargyl-PEG6-acid
- Packaging
- 1g
- Price
- $1240
- Updated
- 2023/06/20
- Product number
- AS104184
- Product name
- Propargyl-PEG5-CH2CH2COOH
- Purity
- 95+%
- Packaging
- 5G
- Price
- $1478
- Updated
- 2021/12/16
- Product number
- BIPG1707
- Product name
- Propargyl-PEG6-acid
- Packaging
- 100mg
- Price
- $507
- Updated
- 2021/12/16
- Product number
- AS104184
- Product name
- Propargyl-PEG5-CH2CH2COOH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $583
- Updated
- 2021/12/16
Propargyl-PEG6-acid Chemical Properties,Usage,Production
Description
Propargyl-PEG6-acid comprises propargyl and carboxylic acid functional groups. The acid group reacts with primary amines in the presence of activators (e.g. EDC, or HATU).The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The molecule has good solubility in aqueous environment.
Uses
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG6-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
Propargyl-PEG6-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG6-acid Suppliers
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View Lastest Price from Propargyl-PEG6-acid manufacturers
- Product
- Propargyl-peg6-acid 1951438-84-8
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-07
- Product
- Propargyl-PEG6-acid 1951438-84-8
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26