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Propargyl-PEG6-acid

Product Name
Propargyl-PEG6-acid
CAS No.
1951438-84-8
Chemical Name
Propargyl-PEG6-acid
Synonyms
CAS_1951438-84-8;Propargyl-PEG6-acid;Propargyl-PEG5-C2-COOH;Propyne-PEG5-CH2CH2COOH;Propargyl-PEG5-CH2CH2COOH;Propargyl-PEG6-Propionic Acid;4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid;Propargyl-PEG5-CH2CH2COOH/4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid
CBNumber
CB23134212
Molecular Formula
C16H28O8
Formula Weight
348.39
MOL File
1951438-84-8.mol
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Propargyl-PEG6-acid Property

Boiling point:
462.8±45.0 °C(Predicted)
Density 
1.126±0.06 g/cm3(Predicted)
refractive index 
n/D 1.469
storage temp. 
-20°C
solubility 
Soluble in Water
form 
liquid
pka
4.28±0.10(Predicted)
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902667
Product name
Propargyl-PEG6-acid
Packaging
250mg
Price
$482
Updated
2024/03/01
Sigma-Aldrich
Product number
902667
Product name
Propargyl-PEG6-acid
Packaging
1g
Price
$1240
Updated
2023/06/20
Activate Scientific
Product number
AS104184
Product name
Propargyl-PEG5-CH2CH2COOH
Purity
95+%
Packaging
5G
Price
$1478
Updated
2021/12/16
Apolloscientific
Product number
BIPG1707
Product name
Propargyl-PEG6-acid
Packaging
100mg
Price
$507
Updated
2021/12/16
Activate Scientific
Product number
AS104184
Product name
Propargyl-PEG5-CH2CH2COOH
Purity
95+%
Packaging
1g
Price
$583
Updated
2021/12/16
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Propargyl-PEG6-acid Chemical Properties,Usage,Production

Description

Propargyl-PEG6-acid comprises propargyl and carboxylic acid functional groups. The acid group reacts with primary amines in the presence of activators (e.g. EDC, or HATU).The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The molecule has good solubility in aqueous environment.

Uses

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG6-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Propargyl-PEG6-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG6-acid Suppliers

Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7195
Advantage
65
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
3980
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28806
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4825
Advantage
58
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View Lastest Price from Propargyl-PEG6-acid manufacturers

airuikechemical co., ltd.
Product
Propargyl-peg6-acid 1951438-84-8
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-07
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG6-acid 1951438-84-8
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26

1951438-84-8, Propargyl-PEG6-acidRelated Search:


  • Propargyl-PEG6-acid
  • Propyne-PEG5-CH2CH2COOH
  • Propargyl-PEG5-CH2CH2COOH
  • CAS_1951438-84-8
  • 4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid
  • Propargyl-PEG6-Propionic Acid
  • Propargyl-PEG5-CH2CH2COOH/4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid
  • Propargyl-PEG5-C2-COOH
  • 1951438-84-8
  • peg