Propargyl-PEG10-acid
- Product Name
- Propargyl-PEG10-acid
- CAS No.
- 2055022-18-7
- Chemical Name
- Propargyl-PEG10-acid
- Synonyms
- CAS_2055022-18-7;Propargyl-PEG10-acid;Propargyl-PEG9-C2-COOH;Propargyl-PEG9-CH2CH2COOH;4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacont-33-ynoic acid;Propargyl-PEG9-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacont-33-ynoic acid;3-[2-[2-[2-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
- CBNumber
- CB13134194
- Molecular Formula
- C24H44O12
- Formula Weight
- 524.6
- MOL File
- 2055022-18-7.mol
Propargyl-PEG10-acid Property
- Boiling point:
- 593.9±50.0 °C(Predicted)
- Density
- 1.124±0.06 g/cm3(Predicted)
- storage temp.
- Store at Room Tem.
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 4.28±0.10(Predicted)
- form
- Liquid (Density: 1.124±0.06 g/cm3)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-22822
- Product name
- Propargyl-PEG10-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- BP-22822
- Product name
- Propargyl-PEG10-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- BIPG1710
- Product name
- Propargyl-PEG10-acid
- Packaging
- 100mg
- Price
- $565
- Updated
- 2021/12/16
- Product number
- AS104188
- Product name
- Propargyl-PEG9-CH2CH2COOH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $721
- Updated
- 2021/12/16
- Product number
- BP-22822
- Product name
- Propargyl-PEG10-acid
- Purity
- 98%
- Packaging
- 500mg
- Price
- $850
- Updated
- 2021/12/16
Propargyl-PEG10-acid Chemical Properties,Usage,Production
Description
Propargyl-PEG10-acid is a propargyl PEG linker with a terminal carboxylic acid. The terminal carboxylic acid forms amide bonds with primary amines; activators (EDC or HATU) will be needed. The propargyl group can react with azide-bearing compounds to form stable triazole bonds.
Uses
Propargyl-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG10-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG10-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG10-acid Suppliers
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- 400-164-7117 13681763483
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- +86-21-61629029
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- 0411-39042693
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- 0371-55055611 18137792234
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- QQ：3002694073
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- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
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View Lastest Price from Propargyl-PEG10-acid manufacturers
- Product
- Propargyl-PEG9-CH2CH2COOH 2055022-18-7
- Price
- US $1551.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-24
- Product
- Propargyl-PEG10-acid 2055022-18-7
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26