Propargyl-PEG10-t-butyl ester
- Product Name
- Propargyl-PEG10-t-butyl ester
- CAS No.
- 2055022-22-3
- Chemical Name
- Propargyl-PEG10-t-butyl ester
- Synonyms
- CAS_2055022-22-3;Propargyl-PEG10-Boc;Propargyl-PEG10-COOtBu;Propargyl-PEG9-C2-COOtBu;Propargyl-PEG10-t-Bu Ester;Propargyl-PEG9-CH2CH2COOtBu;Propargyl-PEG10-t-butyl ester;Propyne decapolyethylene glycol tert butyl propionate;tert-Butyl 4,7,10,13,16,19,22,25,28,31-decaoxatetratriacont-33-ynoate;4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacont-33-ynoic acid, 1,1-dimethylethyl ester
- CBNumber
- CB73134196
- Molecular Formula
- C28H52O12
- Formula Weight
- 580.71
- MOL File
- 2055022-22-3.mol
Propargyl-PEG10-t-butyl ester Property
- Boiling point:
- 592.3±45.0 °C(Predicted)
- Density
- 1.072±0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DCM, DMF
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-22819
- Product name
- Propargyl-PEG10-t-butylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BIPG1750
- Product name
- Propargyl-PEG10-t-butyl ester
- Packaging
- 100mg
- Price
- $546
- Updated
- 2021/12/16
- Product number
- BP-22819
- Product name
- Propargyl-PEG10-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $645
- Updated
- 2021/12/16
- Product number
- AS107832
- Product name
- Propargyl-PEG9-CH2CH2COOtBu
- Purity
- 97%
- Packaging
- 1g
- Price
- $869
- Updated
- 2021/12/16
- Product number
- B-1482
- Product name
- Propargyl-PEG9-CH2CH2COOtBu
- Purity
- 97%
- Packaging
- 1g
- Price
- $605
- Updated
- 2021/12/16
Propargyl-PEG10-t-butyl ester Chemical Properties,Usage,Production
Description
Propargyl-PEG10-t-butyl ester is a crosslinking reagent that can react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. The carboxyl group can be deprotected under acidic conditions.
Uses
Propargyl-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG10-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG10-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Propargyl-PEG10-t-butyl ester manufacturers
- Product
- Propargyl-PEG10-COOtBu 2055022-22-3
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-03
- Product
- Propargyl-PEG10-COOtBu 2055022-22-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 10g
- Release date
- 2024-03-26