ChemicalBook > CAS DataBase List > Propargyl-PEG13-acid

Propargyl-PEG13-acid

Product Name
Propargyl-PEG13-acid
CAS No.
1421676-62-1
Chemical Name
Propargyl-PEG13-acid
Synonyms
CAS_1421676-62-1;Propargyl-PEG-acid;Propargyl-PEG25-acid;Propargyl-PEG13-acid;Propargyl-PEG12-CH2CH2COOH;Poly(oxy-1,2-ethanediyl), α-(2-carboxyethyl)-ω-(2-propyn-1-yloxy)-
CBNumber
CB73134202
Molecular Formula
(C2H4O)nC6H8O3
Formula Weight
0
MOL File
1421676-62-1.mol
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Propargyl-PEG13-acid Property

solubility 
Soluble in Water, DMSO, DCM, DMF
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P839555
Product name
Propargyl-PEG14-acid
Packaging
5mg
Price
$65
Updated
2021/12/16
BroadPharm
Product number
BP-22597
Product name
Propargyl-PEG13-acid
Purity
98%
Packaging
100mg
Price
$320
Updated
2021/12/16
BroadPharm
Product number
BP-22855
Product name
Propargyl-PEG14-acid
Purity
98%
Packaging
100mg
Price
$350
Updated
2021/12/16
BroadPharm
Product number
BP-22998
Product name
Propargyl-PEG25-acid
Purity
97%
Packaging
50mg
Price
$450
Updated
2021/12/16
Apolloscientific
Product number
BIPG1711
Product name
Propargyl-PEG13-acid
Packaging
100mg
Price
$623
Updated
2021/12/16
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Propargyl-PEG13-acid Chemical Properties,Usage,Production

Description

Propargyl-PEG13-acid consists of an alkyne group and a carboxylic acid. The carboxylic acid reacts with amine groups to form amide bonds in the presence of EDC or HATU as an activator. The alkyne group is commonly used in copper catalyzed azide-alkyne Click Chemistry reactions. The hydrophilic PEG units enhance the solubility of the molecule in aqueous media.

Uses

Propargyl-PEG-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Propargyl-PEG13-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG13-acid Suppliers

Alabiochem Tech.Co., Ltd.
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View Lastest Price from Propargyl-PEG13-acid manufacturers

LAURENT
Product
Propargyl-PEG12-CH2CH2COOH 1421676-62-1
Price
US $2463.00/g
Min. Order
1g
Purity
98%
Supply Ability
500kg
Release date
2025-11-24
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG14-acid 1421676-62-1
Price
US $0.00/g
Min. Order
1g
Purity
>95.00%
Supply Ability
1g
Release date
2024-03-28
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG13-acid 1421676-62-1
Price
US $0.00/g
Min. Order
1g
Purity
>95.00%
Supply Ability
1g
Release date
2024-03-26