Propargyl-PEG9-bromide
- Product Name
- Propargyl-PEG9-bromide
- CAS No.
- 2055042-83-4
- Chemical Name
- Propargyl-PEG9-bromide
- Synonyms
- Alkyne-PEG9-Br;Propargyl-PEG9-Br;Propargyl-PEG9-bromide;1-Bromo-3,6,9,12,15,18,21,24,27-nonaoxatriacont-29-yne;3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yne, 1-bromo-;Propargyl-PEG9-Br/3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yne, 1-bromo-
- CBNumber
- CB83163120
- Molecular Formula
- C21H39BrO9
- Formula Weight
- 515.43
- MOL File
- 2055042-83-4.mol
Propargyl-PEG9-bromide Property
- Boiling point:
- 525.6±45.0 °C(Predicted)
- Density
- 1.200±0.06 g/cm3(Predicted)
N-Bromosuccinimide Price
- Product number
- BP-23120
- Product name
- Propargyl-PEG9-bromide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- B-1400
- Product name
- Propargyl-PEG9-Br
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $293.3
- Updated
- 2021/12/16
- Product number
- B-1400
- Product name
- Propargyl-PEG9-Br
- Purity
- 97%
- Packaging
- 1g
- Price
- $660
- Updated
- 2021/12/16
Propargyl-PEG9-bromide Chemical Properties,Usage,Production
Description
Propargyl-PEG9-bromide consists of a propargyl group and a bromide group. The propargyl group reacts with azide compounds in copper catalyzed Click Chemistry reactions. The bromide (Br)can be used as a leaving group for nucleophilic substitution reactions. The 9-unit PEG spacer improves the hydrophilicity of the molecule.
Uses
Propargyl-PEG9-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG9-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG9-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Non-cleavable Linker; PEGs
References
[1] Suzanne AKERS-RODRIGUEZ, et al. Compositions and methods for the treatment of bacterial infections. WO2019126353A2.
Propargyl-PEG9-bromide Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG9-bromide Suppliers
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View Lastest Price from Propargyl-PEG9-bromide manufacturers
- Product
- Propargyl-PEG9-bromide 2055042-83-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26