Aminoxy-PEG3-Propargyl
- Product Name
- Aminoxy-PEG3-Propargyl
- CAS No.
- 1807537-27-4
- Chemical Name
- Aminoxy-PEG3-Propargyl
- Synonyms
- Aminoxy-PEG3-Alkyne;Aminooxy-PEG3-Alkyne;Aminoxy-PEG3-Propargyl;Aminooxy-PEG3-Propargyl;Aminoxy-triethylene glycol-propynyl;O-(2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)hydroxylamine;Hydroxylamine, O-[2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]ethyl]-
- CBNumber
- CB73062329
- Molecular Formula
- C9H17NO4
- Formula Weight
- 203.24
- MOL File
- 1807537-27-4.mol
Aminoxy-PEG3-Propargyl Property
- Boiling point:
- 309.6±32.0 °C(Predicted)
- Density
- 1.069±0.06 g/cm3(Predicted)
- pka
- 4.21±0.70(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H227Combustible liquid
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H332Harmful if inhaled
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P370+P378In case of fire: Use … for extinction.
P403Store in a well-ventilated place.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A578845
- Product name
- Aminoxy-PEG3-propargyl
- Packaging
- 5mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- A578845
- Product name
- Aminoxy-PEG3-propargyl
- Packaging
- 10mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- BIPG1086
- Product name
- Aminoxy-PEG3-Propargyl
- Packaging
- 100mg
- Price
- $546
- Updated
- 2021/12/16
Aminoxy-PEG3-Propargyl Chemical Properties,Usage,Production
Description
Aminooxy-PEG3-propargyl has a alkyne group and an aminooxy group. The aminooxy group reacts with aldehydes or ketones to form a stable oxime linkages. The alkyne group can participate in copper catalyzed azide-alkyne Click Chemistry reactions. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Uses
Aminooxy-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Aminooxy-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO2018204416A1.
Aminoxy-PEG3-Propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Aminoxy-PEG3-Propargyl manufacturers
- Product
- Aminooxy-PEG3-propargyl 1807537-27-4
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-22