Benzyl-PEG2-Azide
- Product Name
- Benzyl-PEG2-Azide
- CAS No.
- 1260001-87-3
- Chemical Name
- Benzyl-PEG2-Azide
- Synonyms
- Benzyl-PEG2-N3;CAS_1260001-87-3;Benzyl-PEG2-Azide;2-(2-azidoethoxy)ethoxymethylbenzene;Bn-PEG2-N3/Benzene, [[2-(2-azidoethoxy)ethoxy]methyl]-
- CBNumber
- CB43048687
- Molecular Formula
- C11H15N3O2
- Formula Weight
- 221.26
- MOL File
- 1260001-87-3.mol
Benzyl-PEG2-Azide Property
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- B315793
- Product name
- Benzyl-PEG2-azide
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- BP-22207
- Product name
- Benzyl-PEG2-azide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $380
- Updated
- 2021/12/16
Benzyl-PEG2-Azide Chemical Properties,Usage,Production
Description
Benzyl-PEG2-azide is a PEG linker with an acid labile, benzyl protecting group. The azide can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN moieties. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
Benzyl-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Benzyl-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
References
[1] Steinebach C, et al. A MedChem toolbox for cereblon-directed PROTACs. Medchemcomm. 2019 May 28;10(6):1037-1041. DOI:10.1039/c9md00185a
Benzyl-PEG2-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
Benzyl-PEG2-Azide Suppliers
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View Lastest Price from Benzyl-PEG2-Azide manufacturers
- Product
- Benzyl-PEG2-N3 1260001-87-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25