ChemicalBook > CAS DataBase List > 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL

2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL

Product Name
2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL
CAS No.
24342-68-5
Chemical Name
2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL
Synonyms
Benzyl-PEG6;Benzyl-PEG7;BnO-PEG6-OH;CAS_24342-68-5;HO-(CH2CH2O)6-Bn;HexaethyleneGlycolMonobenzylEther>HEXAETHYLENE GLYCOL MONOBENZYL ETHER;19-Phenyl-3,6,9,12,15,18-hexaoxanonadecan-1-ol;1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-ol;3,6,9,12,15,18-Hexaoxanonadecan-1-ol, 19-phenyl-
CBNumber
CB0243788
Molecular Formula
C19H32O7
Formula Weight
372.45
MOL File
24342-68-5.mol
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2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL Property

Boiling point:
473.6±40.0 °C(Predicted)
Density 
1.097±0.06 g/cm3(Predicted)
refractive index 
1.4920 to 1.4960
storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in DMSO, DCM, DMF
pka
14.36±0.10(Predicted)
form 
clear liquid
color 
Colorless to Light yellow
InChI
InChI=1S/C19H32O7/c20-6-7-21-8-9-22-10-11-23-12-13-24-14-15-25-16-17-26-18-19-4-2-1-3-5-19/h1-5,20H,6-18H2
InChIKey
VVBQKDDPSXBMMZ-UHFFFAOYSA-N
SMILES
C(O)COCCOCCOCCOCCOCCOCC1=CC=CC=C1
CAS DataBase Reference
24342-68-5
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Safety

HS Code 
2909.30.6000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
H1043
Product name
Hexaethylene Glycol Monobenzyl Ether
Purity
>93.0%(GC)
Packaging
1g
Price
$270
Updated
2025/07/31
ChemScene
Product number
CS-0035657
Product name
BnO-PEG6-OH
Packaging
100mg
Price
$83
Updated
2021/12/16
BroadPharm
Product number
BP-22777
Product name
Benzyl-PEG7-alcohol
Purity
98%
Packaging
500mg
Price
$130
Updated
2021/12/16
ChemScene
Product number
CS-0035657
Product name
BnO-PEG6-OH
Packaging
250mg
Price
$138
Updated
2021/12/16
BroadPharm
Product number
BP-22777
Product name
Benzyl-PEG7-alcohol
Purity
98%
Packaging
1g
Price
$210
Updated
2021/12/16
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2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL Chemical Properties,Usage,Production

Description

Benzyl-PEG7-alcohol is a PEG chain containing a benzyl protecing group and a primary alcohol group. The benzyl is an alcohol protecting group and can be removed via hydrogenolysis. The alcohol group can react to further derivatize the compound. The hydrophilic PEG chains increase the water solubility of the compound in aqueous media. Longer PEG chains have better water solubility properties relative to shorter PEG chains.

Uses

BnO-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BnO-PEG6-OH is also a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2].

Biological Activity

BnO-PEG6-OH is a non-cleavable ADC linker containing 6-unit PEG, which can be used to synthesize antibody drug conjugates (ADC). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

target

Non-cleavable

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PEGs

IC 50

Non-cleavable Linker; PEGs

References

[1] Shaoyun Xiang, et al. Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses there. Patent WO2016197946A1.
[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL Suppliers

Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
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981810490@qq.com
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China
ProdList
1566
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58
Wuhan zhuyefeng New Material Co., Ltd
Tel
13554408100
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QQ1523860844
Email
714430008@qq.com
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China
ProdList
121
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58
Borenpharm Co., Ltd
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027-65563561
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86-27-59218822
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sales@borenpharm.com
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China
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1245
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Hebei led the biological technology co., LTD
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0311-89629263; 18032827359
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2922659299@qq.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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PharmaBlock Sciences (Nanjing),Inc.
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025-86918202 4000255188
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86-025-86918232
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sales@pharmablock.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
Fax
86-21-61259102
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market03@meryer.com
Country
China
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40228
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
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86-0571-85151182
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China
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5691
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Beijing Isomersyn Technology CO;LTD
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010-82954736 13391601435
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sales@isomersyn.com
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China
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View Lastest Price from 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL manufacturers

LAURENT
Product
BnO-PEG6-OH 24342-68-5
Price
US $55.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-13
Xian confluore Biological Technology Co., Ltd.
Product
Benzyl-PEG7-alcohol 24342-68-5
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-25
Zhuozhou Wenxi import and Export Co., Ltd
Product
Hexaethylene Glycol Monobenzyl Ether 24342-68-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

24342-68-5, 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOLRelated Search:


  • HEXAETHYLENE GLYCOL MONOBENZYL ETHER
  • 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL
  • BnO-PEG6-OH
  • 1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-ol
  • CAS_24342-68-5
  • 19-Phenyl-3,6,9,12,15,18-hexaoxanonadecan-1-ol
  • Benzyl-PEG7
  • Benzyl-PEG6
  • HexaethyleneGlycolMonobenzylEther&gt
  • 3,6,9,12,15,18-Hexaoxanonadecan-1-ol, 19-phenyl-
  • 2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • HO-(CH2CH2O)6-Bn
  • BnO-PEG6-OH/3,6,9,12,15,18-Hexaoxanonadecan-1-ol, 19-phenyl-
  • 2-[2-[2-[2-[2-(2-benzyloxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol - [B85874]
  • 24342-68-5
  • C19H32O7
  • Monofunctional Ethylene Glycols
  • Ethylene Glycols & Monofunctional Ethylene Glycols
  • Ethylene Glycols & Monofunctional Ethylene Glycols
  • Monofunctional Ethylene Glycols