Benzyl-PEG3-Mes
- Product Name
- Benzyl-PEG3-Mes
- CAS No.
- 150272-33-6
- Chemical Name
- Benzyl-PEG3-Mes
- Synonyms
- Benzyl-PEG2-MS;CAS_150272-33-6;Benzyl-PEG3-Mes;Benzyl-PEG2-Mes;2-(2-(Benzyloxy)ethoxy)ethyl methanesulfonate;2-(2-Phenylmethoxyethoxy)ethyl methanesulfonate;di(ethylene glycol)monobenzyl ether methanesulfonate;Ethanol, 2-[2-(phenylmethoxy)ethoxy]-, methanesulfonate;Ethanol, 2-[2-(phenylmethoxy)ethoxy]-, 1-methanesulfonate
- CBNumber
- CB13049416
- Molecular Formula
- C12H18O5S
- Formula Weight
- 274.33
- MOL File
- 150272-33-6.mol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Benzyl-PEG3-Mes Chemical Properties,Usage,Production
Uses
Benzyl-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Benzyl-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Benzyl-PEG3-Mes Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Benzyl-PEG3-Mes manufacturers
- Product
- Benzyl-PEG2-Ms 150272-33-6
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25