Benzyl-PEG8-THP

Product Name: Benzyl-PEG8-THP
CAS No.: 1611489-00-9
Chemical Name: Benzyl-PEG8-THP
Synonyms: Benzyl-PEG7-THP;Benzyl-PEG9-THP;Benzyl-PEG8-THP;CAS_1611489-00-9;2-((1-Phenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)oxy)tetrahydro-2H-pyran;2H-Pyran, tetrahydro-2-[(25-phenyl-3,6,9,12,15,18,21,24-octaoxapentacos-1-yl)oxy]-
CBNumber: CB93048703
Molecular Formula: C28H48O10
Formula Weight: 544.67
MOL File: 1611489-00-9.mol

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Benzyl-PEG8-THP Property

Boiling point:: 602.0±55.0 °C(Predicted)
Density: 1.11±0.1 g/cm3(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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Benzyl-PEG8-THP Chemical Properties,Usage,Production

Uses

Benzyl-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Benzyl-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Benzyl-PEG8-THP Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzyl-PEG8-THP Suppliers

China 27 United States 1 Global 28

Borenpharm Co., Ltd

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Zhengzhou Acme Chemical Co., Ltd.

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Amatek Scientific Co. Ltd.

Tel: 0512-56316828
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SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
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Henan Alfachem Co.,Ltd.

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Nextpeptide Inc

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Wuhan Borenpharm Co., Ltd

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Shanghai Jiange Chemical Co., Ltd.

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Changsha Bono New Materials Technology Co., Ltd.

Tel: 18191076804
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Country: China
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View Lastest Price from Benzyl-PEG8-THP manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Benzyl-PEG8-THP 1611489-00-9
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-25

1611489-00-9, Benzyl-PEG8-THPRelated Search:

Benzyl-PEG7-alcohol Benzyl-PEG6-azide Nonaethylene glycol Monobenzyl ether Benzyl-PEG2-Azide 2-[2-(BENZYLOXY)ETHOXY]ETHANOL Benzyl-PEG7-amino 2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL Benzyl-PEG3-Mes Benzyl-PEG2-Amino 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL

Benzyl-PEG8-THP

Benzyl-PEG9-THP

Benzyl-PEG7-THP

CAS_1611489-00-9

2H-Pyran, tetrahydro-2-[(25-phenyl-3,6,9,12,15,18,21,24-octaoxapentacos-1-yl)oxy]-

2-((1-Phenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)oxy)tetrahydro-2H-pyran

1611489-00-9