ChemicalBook > CAS DataBase List > Benzyl-PEG2-Azide

Benzyl-PEG2-Azide

Product Name
Benzyl-PEG2-Azide
CAS No.
1260001-87-3
Chemical Name
Benzyl-PEG2-Azide
Synonyms
Benzyl-PEG2-N3;CAS_1260001-87-3;Benzyl-PEG2-Azide;2-(2-azidoethoxy)ethoxymethylbenzene;Bn-PEG2-N3/Benzene, [[2-(2-azidoethoxy)ethoxy]methyl]-
CBNumber
CB43048687
Molecular Formula
C11H15N3O2
Formula Weight
221.26
MOL File
1260001-87-3.mol
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Benzyl-PEG2-Azide Property

storage temp. 
Storage temp. 2-8°C
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B315793
Product name
Benzyl-PEG2-azide
Packaging
10mg
Price
$45
Updated
2021/12/16
BroadPharm
Product number
BP-22207
Product name
Benzyl-PEG2-azide
Purity
98%
Packaging
250mg
Price
$380
Updated
2021/12/16
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Benzyl-PEG2-Azide Chemical Properties,Usage,Production

Description

Benzyl-PEG2-azide is a PEG linker with an acid labile, benzyl protecting group. The azide can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN moieties. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

Benzyl-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Benzyl-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1] Steinebach C, et al. A MedChem toolbox for cereblon-directed PROTACs. Medchemcomm. 2019 May 28;10(6):1037-1041. DOI:10.1039/c9md00185a

Benzyl-PEG2-Azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzyl-PEG2-Azide Suppliers

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View Lastest Price from Benzyl-PEG2-Azide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Benzyl-PEG2-N3 1260001-87-3
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-25