Bromoacetamido-PEG3-t-Butyl Ester

Product Name: Bromoacetamido-PEG3-t-Butyl Ester
CAS No.: 1807537-33-2
Chemical Name: Bromoacetamido-PEG3-t-Butyl Ester
Synonyms: BrCH2CONH-PEG3-COOtBu;Bromoacetamido-PEG3-C2-Boc;Bromoacetamido-PEG3-t-Butyl Ester;tert-butyl 1-bromo-2-oxo-6,9,13-trioxa-3-azahexadecan-16-oate;tert-Butyl 1-bromo-2-oxo-6,9,12-trioxa-3-azapentadecan-15-oate;4,7,10-Trioxa-13-azapentadecanoic acid, 15-bromo-14-oxo-, 1,1-dimethylethyl ester
CBNumber: CB53062431
Molecular Formula: C15H28BrNO6
Formula Weight: 398.29
MOL File: 1807537-33-2.mol

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Bromoacetamido-PEG3-t-Butyl Ester Property

Boiling point:: 507.6±50.0 °C(Predicted)
Density: 1.252±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
pka: 13.20±0.46(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22734
Product name: Bromoacetamido-PEG3-t-butylester
Purity: 98%
Packaging: 250mg
Price: $460
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1319
Product name: Bromoacetamido-PEG3-t-Butyl Ester
Packaging: 100mg
Price: $546
Updated: 2021/12/16

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Bromoacetamido-PEG3-t-Butyl Ester Chemical Properties,Usage,Production

Description

Bromoacetamido-PEG3-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bromoacetamido-PEG3-t-Butyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromoacetamido-PEG3-t-Butyl Ester Suppliers

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View Lastest Price from Bromoacetamido-PEG3-t-Butyl Ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: BrCH2CONH-PEG3-COOtBu 1807537-33-2
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-25

1807537-33-2, Bromoacetamido-PEG3-t-Butyl EsterRelated Search:

Ethane,1,1'-Oxybis〔2-(2-bromoethoxy)- Propargyl-PEG9-bromide Bromoacetamido-PEG4-Acid Propargyl-PEG8-bromide Propargyl-PEG3-Bromide Benzyl-PEG5-Azide Propargyl-PEG4-bromide Bromoacetamido-PEG3-Acid Bromo-PEG4-acid Bromoacetamido-PEG4-t-Butyl Ester Br-PEG6-bromide Bromo-PEG2-phosphonic acid ethyl ester Bromo-PEG5-Azide Bromo-PEG4-Azide Bromo-PEG1-CH2CO2H Bromoacetamido-PEG4-azido NA

BrCH2CONH-PEG3-COOtBu

Bromoacetamido-PEG3-t-Butyl Ester

Bromoacetamido-PEG3-C2-Boc

tert-Butyl 1-bromo-2-oxo-6,9,12-trioxa-3-azapentadecan-15-oate

tert-butyl 1-bromo-2-oxo-6,9,13-trioxa-3-azahexadecan-16-oate

4,7,10-Trioxa-13-azapentadecanoic acid, 15-bromo-14-oxo-, 1,1-dimethylethyl ester

1807537-33-2