Azido-PEG1-CH2CO2tBu

Product Name: Azido-PEG1-CH2CO2tBu
CAS No.: 1820717-35-8
Chemical Name: Azido-PEG1-CH2CO2tBu
Synonyms: CAS_1820717-35-8;Azido-PEG1-C1-Boc;Azido-PEG1-CH2COOtBu;Azido-PEG1-CH2CO2tBu;Azido-PEG1-t-butyl acetate;Azido-PEG1-CH2COOH t-Bu Ester;Azido-PEG1-CH2CO2-t-butyl ester;tert-Butyl 2-(2-azidoethoxy)acetate;Azido-PEG1-CH2CO2-t-Bu,Azido-PEG1-CH2CO2-t-butyl Ester
CBNumber: CB83162860
Molecular Formula: C8H15N3O3
Formula Weight: 201.23
MOL File: 1820717-35-8.mol

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Azido-PEG1-CH2CO2tBu Property

storage temp.: Store at Room Tem.
solubility: Soluble in DCM, DMF

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A965980
Product name: Azido-PEG1-CH2CO2-t-butylEster
Packaging: 5mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-22060
Product name: Azido-PEG1-CH2CO2-t-Bu
Purity: 98%
Packaging: 250mg
Price: $250
Updated: 2021/12/16

Acrotein

Product number: B-0921
Product name: tert-Butyl2-(2-azidoethoxy)acetate
Purity: 97%
Packaging: 1g
Price: $495
Updated: 2021/12/16

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Azido-PEG1-CH2CO2tBu Chemical Properties,Usage,Production

Description

Azido-PEG1-CH2CO2-t-Bu is a azide (N3) containing PEG linker.The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG1-CH2CO2tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG1-CH2CO2tBu Suppliers

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1820717-35-8, Azido-PEG1-CH2CO2tBuRelated Search:

Tetrabutyl titanate Methyl acetate Azido-PEG4-t-butyl acetate Bromo-PEG2-CH2CO2tBu PEG6-(CH2CO2H)2 Hydroxy-PEG6-CH2CO2tBu Bromo-PEG1-CH2CO2tBu Hydroxy-PEG5-t-butyl acetate

Azido-PEG1-CH2CO2tBu

Azido-PEG1-CH2CO2-t-butyl ester

tert-Butyl 2-(2-azidoethoxy)acetate

Azido-PEG1-t-butyl acetate

CAS_1820717-35-8

Azido-PEG1-C1-Boc

Azido-PEG1-CH2CO2-t-Bu,Azido-PEG1-CH2CO2-t-butyl Ester

Azido-PEG1-CH2COOtBu

Azido-PEG1-CH2COOH t-Bu Ester

1820717-35-8