2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI&

Product Name: 2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI&
CAS No.: 26907-54-0
Chemical Name: 2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI&
Synonyms: 2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI&;1,3,4-Thiadiazol-2-aMine, 5-(4-Methylphenyl)-;2-Amino-5-(4-methylphenyl)-1,3,4-thiadiazole 97%;JRH-02705, 5-p-Tolyl-1,3,4-thiadiazol-2-amine, 97%;5-(4-methylphenyl)-1,3,4-thiadiazol-2-amine(SALTDATA: FREE);2-Amino-5-(p-tolyl)-1,3,4-thiadiazole, 5-(p-Tolyl)-1,3,4-thiadiazol-2-amine;5-(4-Methylphenyl)-1,3,4-thiadiazol-2-amine, 5-(p-Tolyl)-1,3,4-thiadiazol-2-amine;4-(5-Amino-1,3,4-thiadiazol-2-yl)toluene, 5-(4-Methylphenyl)-1,3,4-thiadiazol-2-amine
CBNumber: CB2500357
Molecular Formula: C9H9N3S
Formula Weight: 191.25
MOL File: 26907-54-0.mol

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2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI& Property

Melting point:: 218-222 °C
Boiling point:: 364.9±35.0 °C(Predicted)
Density: 1.281±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: solid
pka: 3.11±0.10(Predicted)
Appearance: White to off-white Solid
InChI: 1S/C9H9N3S/c1-6-2-4-7(5-3-6)8-11-12-9(10)13-8/h2-5H,1H3,(H2,10,12)
InChIKey: ZLDPCNCAFSBFCX-UHFFFAOYSA-N
SMILES: Cc1ccc(cc1)-c2nnc(N)s2

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3
HS Code: 2934999090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 663565
Product name: 2-Amino-5-(4-methylphenyl)-1,3,4-thiadiazole
Purity: 97%
Packaging: 5g
Price: $223
Updated: 2022/05/15

Chem-Impex

Product number: 26044
Product name: 2-Amino-5-(4-methylphenyl)-1,3,4-thiadiazole
Purity: ≥97%(HPLC)
Packaging: 1G
Price: $60.39
Updated: 2026/05/19

Chem-Impex

Product number: 26044
Product name: 2-Amino-5-(4-methylphenyl)-1,3,4-thiadiazole
Purity: ≥97%(HPLC)
Packaging: 5G
Price: $230.75
Updated: 2026/05/19

Chem-Impex

Product number: 26044
Product name: 2-Amino-5-(4-methylphenyl)-1,3,4-thiadiazole
Purity: ≥97%(HPLC)
Packaging: 25G
Price: $682.12
Updated: 2026/05/19

Synthonix

Product number: T51742
Product name: 5-(p-Tolyl)-1,3,4-thiadiazol-2-amine
Purity: 95+%
Packaging: 250mg
Price: $24
Updated: 2026/05/06

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2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI& Chemical Properties,Usage,Production

Synthesis

79-19-6

99-94-5

26907-54-0

General procedure for the synthesis of 5-p-tolylphenyl-2-amino-1,3,4-thiadiazole from aminothiourea and p-toluic acid: 5.1.1 Synthesis of 5-(4-morpholinophenyl)-1,3,4-thiadiazol-2-amine (59) 4-Morpholino benzoic acid (5.18 g, 25 mmol) and N-amino thiourea (2.28 g, 25 mmol) were dissolved in POCl3 (7 mL) and stirred vigorously at 75°C for 0.5 hr. After the reaction was completed, H2O (30 mL) was added and the reaction mixture was heated to reflux for 4 hours. Subsequently, the reaction solution was adjusted with 50% NaOH solution to pH 8. The mixture was filtered and the resulting filter cake was recrystallized with ethanol to give 3.90 g of yellow crystalline compound 59 in 59% yield. Compounds 60-81 were synthesized in the same way. 5.1.1.4 Synthesis of 5-(p-tolyl)-1,3,4-thiadiazol-2-amine (63) Yield: 98%, Melting point: 194-195 °C (EtOH). eSI-MS m/z: 192.3 [M + H]+; 1H NMR (DMSO-d6) δ 2.34 (s, 3H), 7.27 (d, J = 8.4 Hz, 2H), 7.35 (s, 2H), 7.64 (d, J = 8.4 Hz, 2H).

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 21, p. 5766 - 5775
[2] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 14, p. 6663 - 6668
[3] European Journal of Medicinal Chemistry, 2015, vol. 95, p. 49 - 63
[4] European Journal of Medicinal Chemistry, 2015, vol. 106, p. 75 - 84
[5] Medicinal Chemistry Research, 2012, vol. 21, # 6, p. 816 - 824

2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI& Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI& Suppliers

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26907-54-0, 2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI&Related Search:

4-(5-AMINO-1,3,4-THIADIAZOL-2-YL)BENZOIC ACID 2-AMINO-5-(4-AMYLPHENYL)-1,3,4-THIADIAZOLE 5-(4-ethylphenyl)-1,3,4-thiadiazol-2-amine 5-(2,4-dimethylphenyl)-1,3,4-thiadiazol-2-amine 5-BIPHENYL-4-YL-[1,3,4]THIADIAZOL-2-YLAMINE 5-(4-methyl-3-nitrophenyl)-1,3,4-thiadiazol-2-amine 2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI& 2-AMINO-5-(4-TERT-BUTYLPHENYL)-1,3,4-THIADIAZOLE 5-(3-methoxy-4-methylphenyl)-1,3,4-thiadiazol-2-amine 4-(5-AMINO-[1,3,4]THIADIAZOL-2-YL)-BENZONITRILE 5-(2,3-dihydro-1H-inden-5-yl)-1,3,4-thiadiazol-2-amine 5-(4-ISOPROPYLPHENYL)-1,3,4-THIADIAZOL-2-AMINE 5-(5-amino-1,3,4-thiadiazol-2-yl)-2-methylphenol 5-(4-TRIFLUOROMETHYL-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE 5-(2,4,6-trimethylphenyl)-1,3,4-thiadiazol-2-amine 5-(3-fluoro-4-methylphenyl)-1,3,4-thiadiazol-2-amine 5-(4-METHYL-3,5-DINITRO-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE 5-(3,4-DIMETHYL-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE

JRH-02705, 5-p-Tolyl-1,3,4-thiadiazol-2-amine, 97%

4-(5-Amino-1,3,4-thiadiazol-2-yl)toluene, 5-(4-Methylphenyl)-1,3,4-thiadiazol-2-amine

2-Amino-5-(4-methylphenyl)-1,3,4-thiadiazole 97%

2-AMINO-5-(4-METHYLPHENYL)-1 3 4-THIADI&

5-(4-Methylphenyl)-1,3,4-thiadiazol-2-amine, 5-(p-Tolyl)-1,3,4-thiadiazol-2-amine

2-Amino-5-(p-tolyl)-1,3,4-thiadiazole, 5-(p-Tolyl)-1,3,4-thiadiazol-2-amine

5-(4-methylphenyl)-1,3,4-thiadiazol-2-amine(SALTDATA: FREE)

1,3,4-Thiadiazol-2-aMine, 5-(4-Methylphenyl)-

26907-54-0