PARAMETHASONE ACETATE (200 MG)
- Product Name
- PARAMETHASONE ACETATE (200 MG)
- CAS No.
- 1597-82-6
- Chemical Name
- PARAMETHASONE ACETATE (200 MG)
- Synonyms
- dilar;Dillar;Stemex;C12656;Metilar;alondra;haldrate;haldrone;cortidene;Syntecort
- CBNumber
- CB2500519
- Molecular Formula
- C24H31FO6
- Formula Weight
- 434.4977432
- MOL File
- 1597-82-6.mol
PARAMETHASONE ACETATE (200 MG) Property
- Melting point:
- 228-241° (dec)
- alpha
- D +85°
- Boiling point:
- 584.2±50.0 °C(Predicted)
- Density
- 1.1517 (estimate)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 12.29±0.70(Predicted)
- color
- Crystals from Me2CO/hexane
- EPA Substance Registry System
- Paramethasone acetate (1597-82-6)
Safety
- Toxicity
- LD50 i.p. in female rats: 392±23 mg/kg (Goldenthal)
N-Bromosuccinimide Price
- Product number
- P191845
- Product name
- ParamethasoneAcetate
- Packaging
- 50mg
- Price
- $1390
- Updated
- 2021/12/16
- Product number
- 60959
- Product name
- ParamethasoneAcetate
- Packaging
- 50mg
- Price
- $2200
- Updated
- 2021/12/16
- Product number
- SHG0006365
- Product name
- PARAMETHASONE ACETATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.17
- Updated
- 2021/12/16
PARAMETHASONE ACETATE (200 MG) Chemical Properties,Usage,Production
Originator
Haldrone,Lilly,US,1961
Uses
Paramethasone Acetate, is a derivative of Dexamethasone (D298800), a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant properties.
Uses
Glucocorticoid.
Definition
ChEBI: Paramethasone acetate is a corticosteroid hormone.
Manufacturing Process
A solution of 0.144 g of the 3-ethylene glycol ketal of 5α,11β,17α,21 tetrahydroxy-6β-fluoro-16α-methylallopregnane-3,20-dione-21 acetate in 12 ml of chloroform and 0.1 ml of absolute alcohol was cooled to -10°C in an icesalt bath and a stream of anhydrous hydrochloric acid was gently bubbled through the solution for 2.5 hours while the temperature was maintained between -5°C and -15°C. The solution was then diluted with 25 ml of chloroform, washed with dilute sodium bicarbonate and water, dried over anhydrous sodium sulfate, and evaporated to dryness under reduced pressure at 60°C or less to give 6α-fluoro-11β,17α,21-trihydroxy-16α-methyl-4-pregnene3,20-dione 21-acetate.
brand name
Haldrone (Lilly).
Therapeutic Function
Glucocorticoid
Safety Profile
Poison by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits toxic fumes of Fí.
PARAMETHASONE ACETATE (200 MG) Preparation Products And Raw materials
Raw materials
Preparation Products
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