Paramethasone

Product Name: Paramethasone
CAS No.: 53-33-8
Chemical Name: Paramethasone
Synonyms: Cortiden;PARAMETHASONE;Picaridin Impurity 9;6a-Fluoro-16a-methylprednisolone;16a-Methyl-6a-fluoroprednisolone;6-alpha-fluoro-16-alpha-methylprednisolone;Methylprednisolone Impurity 30 (Paramethasone);1, 4-PREGNADIEN-6α-FLUORO-16α-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE;6α-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione;6a-fluoro-11b,17a,21-trihydroxy-16a-methyl-1,4-pregnadiene-3,20-dione
CBNumber: CB0301372
Molecular Formula: C22H29FO5
Formula Weight: 392.46
MOL File: 53-33-8.mol

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Paramethasone Property

Melting point:: 228-241°C
Boiling point:: 573.5±50.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 12.34±0.70(Predicted)
color: White to Pale Beige
CAS DataBase Reference: 53-33-8

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Safety

Hazardous Substances Data: 53-33-8(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: P191840
Product name: Paramethasone
Packaging: 2.5mg
Price: $185
Updated: 2021/12/16

TRC

Product number: P191840
Product name: Paramethasone
Packaging: 25mg
Price: $1455
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 60958
Product name: Paramethasone
Packaging: 25mg
Price: $2200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0007268
Product name: PARAMETHASONE
Purity: 95.00%
Packaging: 5G
Price: $909.56
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0007268
Product name: PARAMETHASONE
Purity: 95.00%
Packaging: 10G
Price: $1334.03
Updated: 2021/12/16

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Paramethasone Chemical Properties,Usage,Production

Originator

Haldrone,Lilly,US,1961

Uses

Paramethasone, is a fluorinated glucocorticoid, having anti-inflammatory and immunosuppressant properties.

Uses

Glucocorticoid.

Definition

ChEBI: Paramethasone is a fluorinated steroid.

Manufacturing Process

A solution of 0.144 g of the 3-ethylene glycol ketal of 5α,11β,17α,21 tetrahydroxy-6β-fluoro-16α-methylallopregnane-3,20-dione-21 acetate in 12 ml of chloroform and 0.1 ml of absolute alcohol was cooled to -10°C in an icesalt bath and a stream of anhydrous hydrochloric acid was gently bubbled through the solution for 2.5 hours while the temperature was maintained between -5°C and -15°C. The solution was then diluted with 25 ml of chloroform, washed with dilute sodium bicarbonate and water, dried over anhydrous sodium sulfate, and evaporated to dryness under reduced pressure at 60°C or less to give 6α-fluoro-11β,17α,21-trihydroxy-16α-methyl-4-pregnene3,20-dione 21-acetate.

brand name

Haldrone (Lilly).

Therapeutic Function

Glucocorticoid

Paramethasone Preparation Products And Raw materials

Raw materials

Preparation Products

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Paramethasone Suppliers

China 33 France 1 India 1 United Kingdom 1 United States 12 Global 48

Guangzhou Younan Technology Co., Ltd

Tel: 020-020-82000279 18988968278
Fax: QQ：3283937693
Email: sales@ubiochem.com
Country: China
ProdList: 2357
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
Advantage: 70

ChemStrong Scientific Co.,Ltd

Tel: 0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9972
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

Chengdu HuaNa Chemicals Co., Ltd.

Tel: 028-86612776; 13699069380
Fax: -
Email: 515238037@qq.com
Country: China
ProdList: 963
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55717
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 15093356674;
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30255
Advantage: 58

53-33-8, ParamethasoneRelated Search:

Methylparaben Bensulfuron methyl Kresoxim-methyl Methyl acrylate BECLOMETHASONE Methyl Methylprednisolone Methyl bromide Fluorine paramethasone21-acetat Prednisolone Dexamethasone Fluocortolone Fluprednisolone Paramethasone PARAMETHASONE AC&Eacute PARAMETHASONE ACETATE USP(CRM STANDARD) PARAMETHASONE ACéTATE FPC(CRM STANDARD)

16a-Methyl-6a-fluoroprednisolone

6a-Fluoro-16a-methylprednisolone

Cortiden

Pregna-1,4-diene-3,20-dione, 6a-fluoro-11b,17,21-trihydroxy-16a-methyl- (8CI)

Pregna-1,4-diene-3,20-dione, 6a-fluoro-11b,17,21-trihydroxy-16-methyl- (7CI)

Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)- (9CI)

(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

6α-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione

PARAMETHASONE

6a-fluoro-11b,17a,21-trihydroxy-16a-methyl-1,4-pregnadiene-3,20-dione

6-alpha-fluoro-11-beta,17-alpha,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione

6-alpha-fluoro-16-alpha-methylprednisolone

1,4-PREGNADIEN-6-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE

(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyethanoyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

6-fluoro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16α)-

Pregna-1,4-diene-3,20-dione,6-fluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)-

Methylprednisolone Impurity 30 (Paramethasone)

Picaridin Impurity 9

1, 4-PREGNADIEN-6α-FLUORO-16α-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE

53-33-8