CORALYNE CHLORIDE HYDRATE, 98+%

Product Name: CORALYNE CHLORIDE HYDRATE, 98+%
CAS No.: 38989-38-7
Chemical Name: CORALYNE CHLORIDE HYDRATE, 98+%
Synonyms: nsc96349;(-)-Coralyn chloride;(-)-Coralyne chloride hydrate;coralyne chloride crystalline;CORALYNE CHLORIDE HYDRATE, 98+%;g)quinolizinium,8-methyl-2,3,10,11-tetramethoxy-dibenzo(chloride;8-methyl-2,3,10,11-tetramethoxydibenzo(a,g)quinoliziniumchloride;2,3,10,11-tetramethoxy-8-methyldibenzo[a,g]quinolizinium chloride;cancer,Topoisomerase,inhibit,neurodrug,Inhibitor,Coralyne,Coralyne chloride,Antileukemic,protoberberine,topoisomerase I
CBNumber: CB2500791
Molecular Formula: C22H22ClNO4
Formula Weight: 399.86738
MOL File: 38989-38-7.mol

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CORALYNE CHLORIDE HYDRATE, 98+% Property

Melting point:: 215°C
storage temp.: 2-8°C
solubility: DMSO:5.0(Max Conc. mg/mL);12.5(Max Conc. mM)
Water:5.0(Max Conc. mg/mL);12.5(Max Conc. mM)
form: Solid
color: Light yellow to yellow

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Safety

Hazard Codes: Xi,T
Risk Statements: 36/37/38-25
Safety Statements: 26-36-45
RTECS: HQ1812000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CCH0007261
Product name: (-)-CORALYNE CHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $503.1
Updated: 2021/12/16

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CORALYNE CHLORIDE HYDRATE, 98+% Chemical Properties,Usage,Production

Chemical Properties

orange crystalline powder

Uses

Coralyne chloride is a protoberberine alkaloid with potent anti-cancer activities. Coralyne chloride acts as a potent topoisomerase I poison and induces Top I mediated DNA cleavage[2]. Coralyne chloride can be used for preparing?coralyne derivatives?as DNA binding fluorescent probes[3].

IC 50

Topoisomerase I

References

[1] Seema Kumari, et al. Synergistic effects of coralyne and paclitaxel on cell migration and proliferation of breast cancer cells lines. Biomed Pharmacother. 2017 Jul;91:436-445. DOI:10.1016/j.biopha.2017.04.027
[2] D Makhey, et al. Coralyne and related compounds as mammalian topoisomerase I and topoisomerase II poisons. Bioorg Med Chem. 1996 Jun;4(6):781-91. DOI:10.1016/0968-0896(96)00054-5
[3] P M Pithan, et al. 8-Styryl-substituted coralyne derivatives as DNA binding fluorescent probes.RSC Adv. 2017 Feb 8;7(18):10660-10667. DOI:10.1039/c6ra27684a

CORALYNE CHLORIDE HYDRATE, 98+% Preparation Products And Raw materials

Raw materials

Preparation Products

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CORALYNE CHLORIDE HYDRATE, 98+% Suppliers

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38989-38-7, CORALYNE CHLORIDE HYDRATE, 98+%Related Search:

Isoquinoline 7-METHOXY-ISOQUINOLINE 6,7-DIMETHOXYISOQUINOLINE 6-Methoxyisoquinoline Isoquinolin-6-ol 7-Hydroxyisoquinoline 1-METHYLISOQUINOLINE CORALYNE CHLORIDE HYDRATE, 98+%

8-methyl-2,3,10,11-tetramethoxydibenzo(a,g)quinoliziniumchloride

g)quinolizinium,8-methyl-2,3,10,11-tetramethoxy-dibenzo(chloride

nsc96349

CORALYNE CHLORIDE HYDRATE, 98+%

coralyne chloride crystalline

2,3,10,11-tetramethoxy-8-methyldibenzo[a,g]quinolizinium chloride

(-)-Coralyne chloride hydrate

cancer,Topoisomerase,inhibit,neurodrug,Inhibitor,Coralyne,Coralyne chloride,Antileukemic,protoberberine,topoisomerase I

(-)-Coralyn chloride

38989-38-7

C22H22ClNO4xH2O

C22H22ClNO4

Alkaloids