Sodium taurodeoxycholate hydrate

Product Name: Sodium taurodeoxycholate hydrate
CAS No.: 207737-97-1
Chemical Name: Sodium taurodeoxycholate hydrate
Synonyms: 5β12αsodium 2-[[(3αSodium taurodeoxycholate, ≥99%;SODIUM TAURODEOXYCHOLATE HYDRATE;N-(Deoxycholyl)taurine sodium salt;SODIUM TAURODEOXYCHOLATE HYDRATE BIO;Taurodeoxycholic acid sodium hydrate;Taurodeoxycholic Acid-[d6] Sodium Salt;2H6]-Taurodeoxycholic Acid Sodium Salt
CBNumber: CB2547459
Molecular Formula: C26H48NNaO7S
Formula Weight: 541.72
MOL File: 207737-97-1.mol

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Sodium taurodeoxycholate hydrate Property

Melting point:: 168 °C (dec.)(lit.)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: H2O: soluble0.5M, clear, colorless to faintly yellow
form: A crystalline solid
color: White to off-white
BRN: 3901204

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Safety

WGK Germany: 3
HS Code: 29242998

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T0557
Product name: Sodium taurodeoxycholate hydrate
Purity: BioXtra, ≥97% (TLC)
Packaging: 1g
Price: $84.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: T0557
Product name: Sodium taurodeoxycholate hydrate
Purity: BioXtra, ≥97% (TLC)
Packaging: 5g
Price: $247
Updated: 2024/03/01

Cayman Chemical

Product number: 15935
Product name: Taurodeoxycholic Acid (sodium salt hydrate)
Purity: ≥95%
Packaging: 1g
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 15935
Product name: Taurodeoxycholic Acid (sodium salt hydrate)
Purity: ≥95%
Packaging: 5G
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 15935
Product name: Taurodeoxycholic Acid (sodium salt hydrate)
Purity: ≥95%
Packaging: 25g
Price: $426
Updated: 2024/03/01

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Sodium taurodeoxycholate hydrate Chemical Properties,Usage,Production

Description

Sodium taurodeoxycholate hydrate is a bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. It has also been used in a study to investigate polymorphic behavior in protein surfactant mixtures.
Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. It has also been used in a study to investigate polymorphic behavior in protein-surfactant mixtures.

Uses

A hydrate form of sodium taurodeoxycholate (T009005), a steroid which rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

General Description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

Purification Methods

The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]

Sodium taurodeoxycholate hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Sodium taurodeoxycholate hydrate Suppliers

Canada 1 China 144 India 9 Switzerland 1 United Kingdom 1 United States 9 USA 1 Global 166

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Thermo Fisher Scientific

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View Lastest Price from Sodium taurodeoxycholate hydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Sodium taurodeoxycholate hydrate 207737-97-1
Price: US $0.00/G
Min. Order: 500G
Purity: 97%min
Supply Ability: 30kg/month
Release date: 2023-02-02

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Taurodeoxycholic Acid Sodium Salt 207737-97-1
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-09-29

R&D Scientific Inc.

Product: Sodium taurodeoxycholate hydrate 207737-97-1
Price: US $550.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-05-07

207737-97-1, Sodium taurodeoxycholate hydrateRelated Search:

Taurohyodeoxycholic acid sodium salt hydrate Taurodeoxycholic acid sodium salt taurohyodeoxycholic acid Sodium taurocholate TAUROHYODEOXYCHOLIC ACID SODIUM SALT TAUROCHOLIC ACID SODIUM SALT HYDRATE TAUROCHENODEOXYCHOLIC ACID SODIUM SALT SODIUM GLYCOCHOLATE HYDRATE, 98 Sodium glycocholate hydrate Glycochenodeoxycholic acid sodium salt Tauroursodeoxycholic acid Ursodeoxycholic acid Sodium cholate Sodium tauroglycocholate Deoxycholic acid Cholic acid

2-[[(3alpha,5beta,12alpha)-3,12-Dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid monosodium salt hydrate

TAURODEOXYCHOLIC ACID SODIUM SIGMAULTRA

2-([3α,12α-dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid

Taurodeoxycholic acid hydrate sodium salt, 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid

N-(Deoxycholyl)taurine sodium salt, Taurodeoxycholic acid sodium salt, 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt

Sodium taurodeoxycholate hydrate,2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate

Ethanesulfonic acid,2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]aMino]-, sodiuM salt, hydrate (1:1:)

Taurodeoxycholic Acid sodium salt hydrat

3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt

N-(Deoxycholyl)taurine sodium salt

2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate

SODIUM TAURODEOXYCHOLATE HYDRATE BIO

Taurodeoxycholic Acid-[d6] Sodium Salt

Taurodeoxycholic acid sodium hydrate

Sodium Taurodeoxycholate Hydrate See T009005

Sodium taurodeoxycholate, ≥99%

Sodium Taurodeoxycholate HydrateQ: What is Sodium Taurodeoxycholate Hydrate Q: What is the CAS Number of Sodium Taurodeoxycholate Hydrate Q: What is the storage condition of Sodium Taurodeoxycholate Hydrate Q: What are the applications of Sodium Taurodeoxycholate Hydrate

Taurodeoxycholic Acid-D4 Sodium Salt DiHydrateQ: What is Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Q: What is the CAS Number of Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Q: What is the storage condition of Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Q: What are the applications of Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate

sodium 2-{[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate hydrate

SODIUM TAURODEOXYCHOLATE HYDRATE

Sodium Taurodeoxycholate Hydrate (STDC Hydrate) extrapure, 97%

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Sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate xhydrate

2H6]-Taurodeoxycholic Acid Sodium Salt

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sodium 2-[[(3&#x3B1

Taurodeoxycholic Acid-[d6] Sodium Salt in Methanol

Taurodeoxycholic Acid Sodium Salt Hydrate in Methanol

207737-97-1

C26H46NO6SxH2ONa