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Sodium taurodeoxycholate hydrate

Product Name
Sodium taurodeoxycholate hydrate
CAS No.
207737-97-1
Chemical Name
Sodium taurodeoxycholate hydrate
Synonyms
Sodium taurodeoxycholate, ≥99%;SODIUM TAURODEOXYCHOLATE HYDRATE;N-(Deoxycholyl)taurine sodium salt;SODIUM TAURODEOXYCHOLATE HYDRATE BIO;Taurodeoxycholic acid sodium hydrate;Taurodeoxycholic Acid-[d6] Sodium Salt;TAURODEOXYCHOLIC ACID SODIUM SIGMAULTRA;Taurodeoxycholic Acid sodium salt hydrat;Sodium Taurodeoxycholate Hydrate See T009005;Sodium Taurodeoxycholate Hydrate (STDC Hydrate) extrapure, 97%
CBNumber
CB2547459
Molecular Formula
C26H48NNaO7S
Formula Weight
541.72
MOL File
207737-97-1.mol
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Sodium taurodeoxycholate hydrate Property

Melting point:
168 °C (dec.)(lit.)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: soluble0.5M, clear, colorless to faintly yellow
form 
A crystalline solid
BRN 
3901204
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Safety

WGK Germany 
3
HS Code 
29242998
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T0557
Product name
Sodium taurodeoxycholate hydrate
Purity
BioXtra, ≥97% (TLC)
Packaging
1g
Price
$84.7
Updated
2024/03/01
Sigma-Aldrich
Product number
T0557
Product name
Sodium taurodeoxycholate hydrate
Purity
BioXtra, ≥97% (TLC)
Packaging
5g
Price
$247
Updated
2024/03/01
Cayman Chemical
Product number
15935
Product name
Taurodeoxycholic Acid (sodium salt hydrate)
Purity
≥95%
Packaging
1g
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
15935
Product name
Taurodeoxycholic Acid (sodium salt hydrate)
Purity
≥95%
Packaging
5G
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
15935
Product name
Taurodeoxycholic Acid (sodium salt hydrate)
Purity
≥95%
Packaging
25g
Price
$426
Updated
2024/03/01
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Sodium taurodeoxycholate hydrate Chemical Properties,Usage,Production

Description

Sodium taurodeoxycholate hydrate is a bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. It has also been used in a study to investigate polymorphic behavior in protein surfactant mixtures.
Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. It has also been used in a study to investigate polymorphic behavior in protein-surfactant mixtures.

Uses

A hydrate form of sodium taurodeoxycholate (T009005), a steroid which rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

General Description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

Purification Methods

The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]

Sodium taurodeoxycholate hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Sodium taurodeoxycholate hydrate Suppliers

Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432 0571-87396433
Fax
0571-87396431
Email
sales@jhechem.com
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China
ProdList
10015
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53
Shanghai Boyle Chemical Co., Ltd.
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021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
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China
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40241
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Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
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China
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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0539-6365991
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3007715519@qq.com
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China
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18736
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Tianjin heowns Biochemical Technology Co., Ltd.
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400 638 7771
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sales@heowns.com
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China
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14443
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Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
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86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
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China
ProdList
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
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0731-85526065 13308475853
Email
ivy@hnhbsj.com
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China
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4531
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Thermo Fisher Scientific
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800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
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China
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17779
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View Lastest Price from Sodium taurodeoxycholate hydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Sodium taurodeoxycholate hydrate 207737-97-1
Price
US $0.00/G
Min. Order
500G
Purity
97%min
Supply Ability
30kg/month
Release date
2023-02-02
Career Henan Chemical Co
Product
Taurodeoxycholic acid sodium salt monohydrate 207737-97-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-13

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