Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester

Product Name: Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester
CAS No.: 843666-34-2
Chemical Name: Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester
Synonyms: Boc-C18-NHS ester;Boc-C16-NHS ester;SemaglutideImpurity7;t-butyl-octadecanedioate-NHS ester;1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester;1-tert-Butyl 18-(2,5-Dioxo-1-pyrrolidinyl) Octadecanedioate;1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate;Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester;Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester（Boc-C16-NHS ester ）
CBNumber: CB25491216
Molecular Formula: C26H45NO6
Formula Weight: 467.64
MOL File: 843666-34-2.mol

More

Less

Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Property

Boiling point:: 537.7±42.0 °C(Predicted)
Density: 1.05±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
form: Solid
color: White to off-white
InChI: InChI=1S/C26H45NO6/c1-26(2,3)32-24(30)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-25(31)33-27-22(28)20-21-23(27)29/h4-21H2,1-3H3
InChIKey: JTOVMMPSILRQQJ-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCCCCCCCCCCCCCCCC(ON1C(=O)CCC1=O)=O

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-24365
Product name: t-butyl-octadecanedioate-NHSester
Purity: 95%
Packaging: 100mg
Price: $180
Updated: 2021/12/16

BroadPharm

Product number: BP-24365
Product name: t-butyl-octadecanedioate-NHSester
Purity: 95%
Packaging: 500mg
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-24365
Product name: t-butyl-octadecanedioate-NHSester
Purity: 95%
Packaging: 1g
Price: $450
Updated: 2021/12/16

Ambeed

Product number: A899034
Product name: 1-tert-Butyl18-(2,5-dioxopyrrolidin-1-yl)octadecanedioate
Purity: 97%
Packaging: 250mg
Price: $220
Updated: 2021/12/16

Ambeed

Product number: A899034
Product name: 1-tert-Butyl18-(2,5-dioxopyrrolidin-1-yl)octadecanedioate
Purity: 97%
Packaging: 1g
Price: $536
Updated: 2021/12/16

More

Less

Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Chemical Properties,Usage,Production

Description

t-butyl-octadecanedioate-NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.

Uses

Boc-C16-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Suppliers

China 51 United States 2 Global 53

Angel Pharmaceuticals Co., Ltd.

Tel: 17305837352
Email: 3900906393@qq.com
Country: China
ProdList: 64
Advantage: 58

Tianjin Chempharmatech Co.,Ltd.

Tel: 022-66211079 13212288319
Fax: qq1405432731
Email: sales@chempharmatech.com
Country: China
ProdList: 915
Advantage: 55

Shanghai Synchem Technology Co., Ltd.

Tel: 021-64502386 18017349250
Email: shsynchem@gmail.com
Country: China
ProdList: 296
Advantage: 60

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9274
Advantage: 55

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-63315541 13323832564
Fax: QQ:3001332135
Email: 3001332135@qq.com
Country: China
ProdList: 9972
Advantage: 58

Abydos Scientific

Tel: 025-84767922 18936879710
Email: sales@abydoscientific.com
Country: China
ProdList: 1002
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Shanghai UCHEM Inc.

Tel: +862156762820 +86-13564624040
Email: sales@myuchem.com
Country: China
ProdList: 8460
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

HUNAN CHEMFISH SCIENTIFIC CO.,LTD

Tel: +86-0731-85567275 13298656710
Fax: QQ:3554193828
Email: sales05@chemfish.com
Country: China
ProdList: 7449
Advantage: 58

More

Less

View Lastest Price from Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD

Product: Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester 843666-34-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2025-09-22

843666-34-2, Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) esterRelated Search:

Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester

Boc-C16-NHS ester

t-butyl-octadecanedioate-NHS ester

1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate

SemaglutideImpurity7

1-tert-Butyl 18-(2,5-Dioxo-1-pyrrolidinyl) Octadecanedioate

1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester

Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester（Boc-C16-NHS ester ）

Boc-C18-NHS ester

843666-34-2

C26H45NO6