Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester
- Product Name
- Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester
- CAS No.
- 843666-34-2
- Chemical Name
- Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester
- Synonyms
- Boc-C18-NHS ester;Boc-C16-NHS ester;SemaglutideImpurity7;t-butyl-octadecanedioate-NHS ester;1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester;1-tert-Butyl 18-(2,5-Dioxo-1-pyrrolidinyl) Octadecanedioate;1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate;Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester;Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester（Boc-C16-NHS ester ）
- CBNumber
- CB25491216
- Molecular Formula
- C26H45NO6
- Formula Weight
- 467.64
- MOL File
- 843666-34-2.mol
Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Property
- Boiling point:
- 537.7±42.0 °C(Predicted)
- Density
- 1.05±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- Solid
- color
- White to off-white
- InChI
- InChI=1S/C26H45NO6/c1-26(2,3)32-24(30)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-25(31)33-27-22(28)20-21-23(27)29/h4-21H2,1-3H3
- InChIKey
- JTOVMMPSILRQQJ-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)CCCCCCCCCCCCCCCCC(ON1C(=O)CCC1=O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-24365
- Product name
- t-butyl-octadecanedioate-NHSester
- Purity
- 95%
- Packaging
- 500mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-24365
- Product name
- t-butyl-octadecanedioate-NHSester
- Purity
- 95%
- Packaging
- 1g
- Price
- $450
- Updated
- 2021/12/16
- Product number
- BP-24365
- Product name
- t-butyl-octadecanedioate-NHSester
- Purity
- 95%
- Packaging
- 100mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- A899034
- Product name
- 1-tert-Butyl18-(2,5-dioxopyrrolidin-1-yl)octadecanedioate
- Purity
- 97%
- Packaging
- 250mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- A899034
- Product name
- 1-tert-Butyl18-(2,5-dioxopyrrolidin-1-yl)octadecanedioate
- Purity
- 97%
- Packaging
- 1g
- Price
- $536
- Updated
- 2021/12/16
Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Chemical Properties,Usage,Production
Description
t-butyl-octadecanedioate-NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.
Uses
Boc-C16-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Preparation Products And Raw materials
Raw materials
Preparation Products
Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
View Lastest Price from Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester manufacturers
- Product
- Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester 843666-34-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2025-09-22