CD19 antibody
Source Reactivity Background References- Product Name
- CD19 antibody
- Chemical Name
- CD19 antibody
- Synonyms
- CD19 antibody
- CBNumber
- CB25524770
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb126667
- Product name
- CD19 antibody
- Purity
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Packaging
- 25μg(Trial Size)
- Price
- $119
- Updated
- 2021/12/16
- Product number
- orb11989
- Product name
- CD19 antibody
- Purity
- Affinity purified
- Packaging
- 100μg
- Price
- $255
- Updated
- 2021/12/16
- Product number
- orb126667
- Product name
- CD19 antibody
- Purity
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Packaging
- 100μg
- Price
- $272
- Updated
- 2021/12/16
- Product number
- orb160312
- Product name
- CD19 antibody
- Purity
- Affinity-purified by affinity-chromatography using epitope-specific immunogen.
- Packaging
- 100μg
- Price
- $280.5
- Updated
- 2021/12/16
- Product number
- orb153340
- Product name
- CD19 antibody
- Purity
- Epitope affinity purified
- Packaging
- 100μg
- Price
- $280.5
- Updated
- 2021/12/16
CD19 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse
Background
CD19 is a 95 kDa coreceptor which amplifies the signaling cascade in B cells. On the B cell surface, CD19 associates with CD21, CD81, and Leu-13 to exert its function. The cytoplasmic tail of CD19 has nine conserved tyrosine residues playing critical roles in CD19 mediated function by coupling signaling molecules to the receptor. After B cell receptor or CD19 ligation, Tyr531 and Tyr500 of CD19 are progressively phosphorylated. This phosphorylation enables the coupling of PI3 kinase and Src family tyrosine kinase to CD19 and activates the PI3K and Src signaling pathways. Coligation of B cell receptor and CD19 also promotes Tyr409 phosphorylation in CD19. The phosphorylation at these sites enables its binding to Vav and mediates elevated intracellular calcium response, as well as the JNK pathway.
References
[1] Tedder, T.F. et al. (1997) Immunity 6, 107-18.
[2] Buhl, A.M. and Cambier, J.C. (1999) J Immunol 162, 4438-46.
[3] Fujimoto, M. et al. (2000) Immunity 13, 47-57.
[4] O'Rourke, L.M. et al. (1998) Immunity 8, 635-45.
[5] Sato, S. et al. (1997) Proc Natl Acad Sci U S A 94, 13158-62.
CD19 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
CD19 antibody Suppliers
- Tel
- 15921930842 15921930842
- yh-wang@univ-bio.com
- Country
- China
- ProdList
- 25004
- Advantage
- 58
- Tel
- 0755-26755892 1-949-553-1900
- international@genetex.com
- Country
- China
- ProdList
- 6092
- Advantage
- 58
- Tel
- 858.663.9055 8586639055
- NSJBioname@qq.com
- Country
- China
- ProdList
- 6941
- Advantage
- 58
- Tel
- Enzo Biochem Inc. 13797054060
- Enzoname@qq.com
- Country
- China
- ProdList
- 6174
- Advantage
- 58
- Tel
- 18886812933
- sales@biosynth.com
- Country
- China
- ProdList
- 6218
- Advantage
- 58
- Tel
- 21-80243558 86218024
- info@cellsignal.cn
- Country
- China
- ProdList
- 6725
- Advantage
- 58
- Tel
- 4006-123-828 13162017139
- market@ab-mart.com
- Country
- China
- ProdList
- 6917
- Advantage
- 58
- Tel
- 025-58868422
- info@sabbiotech.com
- Country
- China
- ProdList
- 6243
- Advantage
- 58
- Tel
- 13047170542
- marketing@fn-test.com
- Country
- China
- ProdList
- 6600
- Advantage
- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58