Myeloperoxidase antibody
Source Reactivity Background References- Product Name
- Myeloperoxidase antibody
- Chemical Name
- Myeloperoxidase antibody
- Synonyms
- Myeloperoxidase antibody
- CBNumber
- CB25664908
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb69136
- Product name
- Myeloperoxidase antibody
- Purity
- Ascitic fluid
- Packaging
- 100μL
- Price
- $370.6
- Updated
- 2021/12/16
- Product number
- orb79334
- Product name
- Myeloperoxidase antibody
- Purity
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Packaging
- 100μg
- Price
- $499.8
- Updated
- 2021/12/16
- Product number
- orb18071
- Product name
- Myeloperoxidase antibody
- Purity
- Immunogen affinity purified.
- Packaging
- 100μg
- Price
- $606.9
- Updated
- 2021/12/16
- Product number
- orb79563
- Product name
- Myeloperoxidase antibody
- Purity
- Affinity purified
- Packaging
- 1mg
- Price
- $642.6
- Updated
- 2021/12/16
- Product number
- orb95686
- Product name
- Myeloperoxidase antibody
- Purity
- Purified
- Packaging
- 50μl
- Price
- $725.9
- Updated
- 2021/12/16
Myeloperoxidase antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse
Background
Myeloperoxidase is a peroxidase enzyme that is part of the host defense system of polymorphonuclear leukocytes. The gene for MPO was cloned independently from several laboratories. A decrease in MPO expression was noticed upon differentiation of HL-60 cells. MPO catalyzes the reaction of hydrogen peroxide and chloride to produce hypochlorous acid and other potent antimicrobial oxidants. Knockout mice of MPO are impaired in clearing select microbial infections. Processing of mature MPO from an initial 80-90 kDa translation product involves insertion of a heme moiety, glycosylation, and proteolytic cleavage. The mature protein is a tetramer of two heavy chains and two light chains. It is abundantly expressed in neutrophils and monocytes and secreted during their activation. Heightened MPO levels have been associated with tissue damage and a number of pathological conditions.
References
[1] Klebanoff, S.J. (2005) J Leukoc Biol 77, 598-625.
[2] Chang, K.S. et al. (1986) Blood 68, 1411-4.
[3] Yamada, M. et al. (1987) Arch Biochem Biophys 255, 147-55.
[4] Morishita, K. et al. (1987) J Biol Chem 262, 3844-51.
[5] Weil, S.C. et al. (1987) Proc Natl Acad Sci USA 84, 2057-61.
[6] Aratani, Y. et al. (2002) J Infect Dis 185, 1833-7.
Myeloperoxidase antibody Preparation Products And Raw materials
Raw materials
Preparation Products
Myeloperoxidase antibody Suppliers
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