PRDX6 antibody
Source Applications Reactivity Immunogen Background References- Product Name
- PRDX6 antibody
- Chemical Name
- PRDX6 antibody
- Synonyms
- PRDX6 antibody;Rabbit Polyclonal PRDX6 Antibody
- CBNumber
- CB25675913
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb178388
- Product name
- PRDX6 antibody
- Purity
- Antigen affinity chromatography
- Packaging
- 100μg
- Price
- $499.8
- Updated
- 2021/12/16
- Product number
- orb94944
- Product name
- PRDX6 antibody
- Purity
- Purified
- Packaging
- 50μl
- Price
- $725.9
- Updated
- 2021/12/16
- Product number
- orb95152
- Product name
- PRDX6 antibody
- Purity
- Ammonium Sulfate Precipitation
- Packaging
- 50μl
- Price
- $725.9
- Updated
- 2021/12/16
- Product number
- orb94945
- Product name
- PRDX6 antibody
- Purity
- Purified
- Packaging
- 50μl
- Price
- $725.9
- Updated
- 2021/12/16
- Product number
- orb96344
- Product name
- PRDX6 antibody
- Purity
- Purified
- Packaging
- 50μl
- Price
- $725.9
- Updated
- 2021/12/16
PRDX6 antibody Chemical Properties,Usage,Production
Source
Rabbit
Applications
PRDX6 antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity.
Reactivity
Human;Mouse;Rat
Immunogen
Anti-human PRDX6 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PRDX6 amino acids 1-224 purified from E. coli.
Background
Peroxiredoxin 6 (PRDX6) belongs to the thiol-specific antioxidant protein family. PRDX6 is a bifunctional enzyme with 2 distinct active sites. PRDX6 is involved in redox regulation of the cell and can reduce Hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. PRDX6 may have a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Furthermore, PRDX6 eases the oxidative stress and TGF-beta-induced abnormalities of human trabecular meshwork cells. In addition, PRDX6 is necessary for blood vessel integrity in injured skin.
At acidic pH, PRDX6 binds to reduced phospholipids, however at cytosolic pH PRDX6 binds only to phospholipids that are oxidized which is compatible with the role for PRDX6 in the repair of peroxidized cell membranes. Hydrogen peroxide-mediated hyperoxidation of PRDX6 induces cell cycle arrest at the G2/M transition via up-regulation of iPLA2 activity. Overexpression of PRDX6 is linked to oligodendroglioma.
References
[1] Kang, S.W. et al. (1998) J Biol Chem 273, 6303-11.
[2] Chen, J.W. et al. (2000) J Biol Chem 275, 28421-7.
[3] Manevich, Y. and Fisher, A.B. (2005) Free Radic Biol Med 38, 1422-32.
[4] Schremmer, B. et al. (2007) Subcell Biochem 44, 317-44.
[5] Lee, S.B. et al. (2009) Mol Cells 28, 583-8.
[6] Ho, J.N. et al. (2010) Mol Cancer Ther 9, 825-32.
[7] Yun, H.M. et al. (2014) Free Radic Biol Med 69, 367-76.
[8] Pak, J.H. et al. (2011) Cancer Invest 29, 21-8.
[9] Kalinina, E.V. et al. (2012) Bull Exp Biol Med 153, 878-81.
[10] Chatterjee, S. et al. (2011) J Biol Chem 286, 11696-706.
PRDX6 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
PRDX6 antibody Suppliers
- Tel
- 18007124176 19384116026
- 2706668885@qq.com
- Country
- China
- ProdList
- 4987
- Advantage
- 58
- Tel
- 027-87196173
- cusabio@163.com
- Country
- China
- ProdList
- 6066
- Advantage
- 58
- Tel
- 027-19371278702 18008634902
- 19384116026@163.com
- Country
- China
- ProdList
- 3008
- Advantage
- 58
- Tel
- Enzo Biochem Inc. 13797054060
- Enzoname@qq.com
- Country
- China
- ProdList
- 6174
- Advantage
- 58
- Tel
- 18886812933
- sales@biosynth.com
- Country
- China
- ProdList
- 6218
- Advantage
- 58
- Tel
- 21-80243558 86218024
- info@cellsignal.cn
- Country
- China
- ProdList
- 6725
- Advantage
- 58
- Tel
- 4006-123-828 13162017139
- market@ab-mart.com
- Country
- China
- ProdList
- 6917
- Advantage
- 58
- Tel
- 025-58868422
- info@sabbiotech.com
- Country
- China
- ProdList
- 6243
- Advantage
- 58
- Tel
- 13047170542
- marketing@fn-test.com
- Country
- China
- ProdList
- 6600
- Advantage
- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58