RAB11A Antibody
Source Reactivity Background References- Product Name
- RAB11A Antibody
- Chemical Name
- RAB11A Antibody
- Synonyms
- RAB11A Antibody
- CBNumber
- CB25677841
- Formula Weight
- 0
- MOL File
- Mol file
RAB11A Antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Background
Rab11a, Rab11b and Rab25 are members of the Rab11 family of small Ras-like GTPases. Rab11 functions as a key regulator in the recycling of perinuclear, plasma membrane and Golgi compartment endosomes. Despite some overlap, distinct differences exist between Rab11a and Rab11b in both their cellular distribution and functional roles. Rab11a is ubiquitously expressed while Rab11b is found mainly in the heart and brain. Like other Rab proteins, Rab11 exerts its function via interactions with Rab11 family interacting proteins. While there are three distinct classes of FIPs, all appear to share a conserved carboxy-terminal Rab-binding domain that allows Rab-FIP protein interaction. When bound together, these proteins are thought to regulate membrane-associated protein sorting.
References
[1] Ullrich, O. et al. (1996) J. Cell Biol. 135, 913-924.
[2] Chen, W. et al. (1998) Mol. Biol. Cell 9, 3241-3257.
[3] Lapierre, L.A. et al. (2003) Exp. Cell Res. 290, 322-331.
[4] Khvotchev, M.V. et al. (2003) J. Neurosci. 23, 10531-10539.
[5] Junutula, J.R. et al. (2004) J. Biol. Chem. 279, 33430-33437.
[6] Hales, C.M. et al. (2001) J. Biol. Chem. 276, 39067-39075.
RAB11A Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
RAB11A Antibody Suppliers
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