Description Reactivity Immunogen Background

REG3A Antibody

Description Reactivity Immunogen Background
Product Name
REG3A Antibody
Chemical Name
REG3A Antibody
Synonyms
REG3A Antibody
CBNumber
CB25691744
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb221882
Product name
Reg3a antibody
Purity
Affinity purified by Protein A
Packaging
100μg
Price
$421.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb221883
Product name
Reg3a antibody
Purity
Affinity purified by Protein A
Packaging
100μg
Price
$421.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb221882
Product name
Reg3a antibody
Purity
Affinity purified by Protein A
Packaging
200μg
Price
$673.2
Updated
2021/12/16
Biorbyt Ltd
Product number
orb2701
Product name
Reg3a antibody
Purity
Affinity purified by Protein A
Packaging
200μg
Price
$673.2
Updated
2021/12/16
Biorbyt Ltd
Product number
orb221883
Product name
Reg3a antibody
Purity
Affinity purified by Protein A
Packaging
200μg
Price
$673.2
Updated
2021/12/16
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REG3A Antibody Chemical Properties,Usage,Production

Description

The Antibody was raised in rabbits by immunization with the recombinant human REG3A. The amino acid sequence of the recombinant human REG3A is 100% homologus to the amino acid sequence of the human REG3A sequence. The immunization antigen is the 18.4 kDa protein containing 149 amino acid residues- His Tag.

Reactivity

Human

Immunogen

MRGSHHHHHH GMASHMEEPQ RELPSARIRC PKGSKAYGSH CYALFLSPKS WTDADLACQK RPSGNLVSVL SGAEGSFVSS LVKSIGNSYS YVWIGLHDPT QGTEPNGEGW EWSSSDVMNY FAWERNPSTI SSPGHCASLS RSTAFLRWKD YNCNVRLPYV CKFTD.

Background

Pancreatitis-associated protein (PAP) is a secretory protein not normally expressed in healthy pancreas but highly induced during acute pancreatitis. While PAP has been shown to be anti-bacterial and antiapoptotic in vitro, its definitive biological function in vivo is not clear. Using antisepse oligonucleotides, inhibition of PAP expression significantly worsened pancreatitis in a rat model. During pancreatitis, PAP released by the pancreas could mediate lung inflammation through induction of hepatic TNF- alpha expression and subsequent increase in circulating TNF-alpha.
PAP is activated in primary liver cancers. In normal liver, the protein is undetectable in normal mature hepatocytes and found only in some ductular cells, representing potential hepatic progenitor cells. PAP can be considered hepatic cytokine that combines mitogenic and anti-apoptotic functions regarding hepatocytes, and consequently acts as a growth factor in vivo to enhance liver regeneration. In pancreatic cancor, PAP was overexpressed in 79% (30 of 38) of pancreatic ductal adenocarcinoma, 19% (7 of 36) of chronic pancreatitis, and 29% (2 of 7) of mucinous cystadenoma. PAP was found in malignant ductular structures in pancreatic carcinomas as well as in benign proliferating ductules and acinar cells in chronic pancreatitis. Elevation of PAP in patients with pancreatic cancer is not merely explainable by concomitant pancreatitis, but seems to be due to increased PAP production by the cancer cells and is also correlated to tumour load as expressed by the UICC stages.
Epithelial expression of PAP was induced under intestinal mucosal inflammation initiated by exposure to commensal bacteria or DSS as well as inflamed IBD colon. Increased serum level of PAP diagnosed ileal location in active Crohn disease with a sensitivity of 60%, a specificity of 94%, a positive predictive value of 84% and a negative predictive value of 81%. Elevated serum PAP (> 50 ng/mL) is significantly associated with disease activity and ileal location of Crohn disease.

REG3A Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

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REG3A Antibody Suppliers

Absin Bioscience Inc.
Tel
021-38015121 18438616290
Email
lanwu@univ-bio.com
Country
China
ProdList
24731
Advantage
58
Hubei Ipodix Biotechnology Co.,Ltd.
Tel
18007124176 19384116026
Email
2706668885@qq.com
Country
China
ProdList
4987
Advantage
58
Novus Biologicals
Tel
400821347
Email
orders@novusbio.com
Country
China
ProdList
6433
Advantage
58
CUSABIO TECHNOLOGY LLC
Tel
027-87196173
Email
cusabio@163.com
Country
China
ProdList
6066
Advantage
58
Hubei Serenity BioSolutions Co., Ltd.
Tel
027-19371278702 18008634902
Email
19384116026@163.com
Country
China
ProdList
3008
Advantage
58
Enzo Biochem Inc
Tel
Enzo Biochem Inc. 13797054060
Email
Enzoname@qq.com
Country
China
ProdList
6174
Advantage
58
Biosynth Ltd
Tel
18886812933
Email
sales@biosynth.com
Country
China
ProdList
6218
Advantage
58
Abmart Inc
Tel
4006-123-828 13162017139
Email
market@ab-mart.com
Country
China
ProdList
6917
Advantage
58
Signalway Antibody LLC
Tel
025-58868422
Email
info@sabbiotech.com
Country
China
ProdList
6243
Advantage
58
Wuhan Fine Biotech Co Ltd
Tel
13047170542
Email
marketing@fn-test.com
Country
China
ProdList
6600
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Adooq Bioscience LLC
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58
ProSpec Tany TechnoGene Ltd
Tel
972-8947-1175
Email
info@prospecbio.com
Country
China
ProdList
6874
Advantage
58
Rockland Immunochemicals Inc
Tel
0512-65829739
Email
antibodies-onlinename@qq.com
Country
China
ProdList
0
Advantage
58
Shenzhen 10:30 Trading Co., Ltd.
Tel
18665911837
Country
CHINA
ProdList
100
Advantage
58
Neobioscience Co., Ltd.
Tel
--
Fax
--
Email
info@neobioscience.com
Country
CHINA
ProdList
6207
Advantage
58
Biorbyt Ltd.
Tel
--
Fax
--
Email
info@biorbyt.com
Country
CHINA
ProdList
6482
Advantage
58
Shanghai Qunji Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6971
Advantage
58
Shanghai Qingmu Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6826
Advantage
58
Shenyang Wanteng Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
wantengbio@163.com
Country
CHINA
ProdList
6674
Advantage
58
Shanghai Fushen Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
jsyz216@163.com
Country
CHINA
ProdList
6547
Advantage
58
Shanghai Yaoyun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
912529879@qq.com
Country
CHINA
ProdList
6448
Advantage
58
Shanghai Huzhen Industrial Co., Ltd.
Tel
--
Fax
--
Email
shhzsw01@163.com
Country
CHINA
ProdList
6477
Advantage
58
Nanjing Laifusai Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@lifescimall.com
Country
CHINA
ProdList
6638
Advantage
58
Beijing Chief-East Tech Co.,Ltd (Qwbio)
Tel
--
Fax
--
Email
info@qwbio.com
Country
China
ProdList
6912
Advantage
50
Beijing Bai Ao Si Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
yangmei@bioneeds.net
Country
CHINA
ProdList
6999
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
market@xlswkj.com
Country
CHINA
ProdList
6793
Advantage
58
Beijing Bomais Technology Development Co., Ltd.
Tel
--
Fax
--
Email
15210716102@139.com
Country
CHINA
ProdList
6274
Advantage
58
Beijing Jiamei Zhenyuan Biotechnology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6403
Advantage
58
Miaotong (Shanghai) Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
hmzhang@mt-bio.com
Country
CHINA
ProdList
6909
Advantage
58
Beijing Huaxia Ocean Technology Co., Ltd.
Tel
--
Fax
--
Email
huaxiabio@163.com
Country
CHINA
ProdList
6122
Advantage
58
Wuhan Boot Biotechnology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6829
Advantage
58
Beijing Dakco is Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
bj_info@dakewe.net
Country
CHINA
ProdList
6580
Advantage
58
Changzhou Xiangtai Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
order@affbiotech.com
Country
CHINA
ProdList
6801
Advantage
58
Xiamen Research Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1562893815@qq.com
Country
CHINA
ProdList
6936
Advantage
58
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1985563437@qq.com
Country
CHINA
ProdList
6525
Advantage
58
Boao Pike
Tel
--
Fax
--
Email
lyn@biopike.com.cn
Country
CHINA
ProdList
6646
Advantage
58
Nanjing Enjing Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2426321791@qq.com
Country
CHINA
ProdList
5118
Advantage
58
Shanghai Yubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
shybio@126.com
Country
CHINA
ProdList
6966
Advantage
58
Shanghai Lianmai Biological Engineering Co., Ltd.
Tel
--
Fax
--
Email
shlmai@163.com
Country
CHINA
ProdList
6055
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6170
Advantage
58
Shanghai Lianshuobao is Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
lianshuobio@163.com
Country
CHINA
ProdList
6984
Advantage
58
Shanghai Yuqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
847627550@qq.com
Country
CHINA
ProdList
6087
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6906
Advantage
58
Bsno (Tianjin) Biotechnology Co., Ltd
Tel
--
Fax
--
Email
1073531646@qq.com
Country
CHINA
ProdList
6571
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58