VRK3 Antibody
Source Reactivity Background References- Product Name
- VRK3 Antibody
- Chemical Name
- VRK3 Antibody
- Synonyms
- VRK3 Antibody
- CBNumber
- CB25704747
- Formula Weight
- 0
- MOL File
- Mol file
VRK3 Antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Background
The vaccinia-related kinase proteins are a new group of Ser/Thr kinases in the human kinome. This mammalian kinase family comprises three members, VRK1, VRK2, and VRK3. The VRK1 has autophosphorylation activity and phosphorylates several transcription factors, including p53, ATF2, and c-Jun. VRK2 is associated with the endoplasmic reticulum. VRK3 suppresses Erk activity through direct interaction and activation of the MAP kinase phosphatase VHR. Further functional and structural analysis of VRK proteins will elucidate important new aspects of cell regulation.
References
[1] Nezu, J. et al. (1997) Genomics 45, 327-31.
[2] Zelko, I. et al. (1998) Arch Biochem Biophys 352, 31-6.
[3] Vega, F.M. et al. (2003) FEBS Lett 544, 176-80.
[4] Lopez-Borges, S. and Lazo, P.A. (2000) Oncogene 19, 3656-64.
[5] Sevilla, A. et al. (2004) J Biol Chem 279, 27458-65.
[6] Sevilla, A. et al. (2004) Oncogene 23, 8950-8.
[7] Nichols, R.J. and Traktman, P. (2004) J Biol Chem 279, 7934-46.
[8] Kang, T.H. and Kim, K.T. (2006) Nat Cell Biol 8, 863-9.
VRK3 Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
VRK3 Antibody Suppliers
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