ChemicalBook > CAS DataBase List > (S)-BAY-293

(S)-BAY-293

Product Name
(S)-BAY-293
CAS No.
2244904-69-4
Chemical Name
(S)-BAY-293
Synonyms
BAY 294;(S)-BAY-293;BAY 293 Negative Control;4-Quinazolinamine, 6,7-dimethoxy-2-methyl-N-[(1S)-1-[4-[2-[(methylamino)methyl]phenyl]-2-thienyl]ethyl]-
CBNumber
CB25867497
Molecular Formula
C25H28N4O2S
Formula Weight
448.58
MOL File
2244904-69-4.mol
More
Less

(S)-BAY-293 Property

Boiling point:
553.4±50.0 °C(Predicted)
Density 
1.218±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
9.61±0.10(Predicted)
form 
Solid
color 
White to off-white
optical activity
[α]/D +86.0 to +106.0°, c =1.0 in DMSO
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
6906
Product name
BAY293NegativeControl
Purity
≥98%(HPLC)
Packaging
5
Price
$235
Updated
2021/12/16
More
Less

(S)-BAY-293 Chemical Properties,Usage,Production

Biological Activity

BAY-294 corresponds to the (S)-enantiomer of and the recommended control for the selective SOS1-KRAS interaction inhibitor BAY-293 (IC50 = 2.34 μM/BAY-294 vs. 21 nM/BAY-293; 10 nM hSOS1c at & 5 nM hKRAS G12C). BAY-294 exhibits little potency against SOS1-mediated KRAS activation (IC50 = 3.91 μM/BAY-294 vs. 52 nM/BAY-293; 10 nM SOS1c at & 50 nM wt hKRAS).

storage

Store at -20°C

(S)-BAY-293 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(S)-BAY-293 Suppliers

Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58

2244904-69-4, (S)-BAY-293Related Search:


  • (S)-BAY-293
  • BAY 293 Negative Control
  • 4-Quinazolinamine, 6,7-dimethoxy-2-methyl-N-[(1S)-1-[4-[2-[(methylamino)methyl]phenyl]-2-thienyl]ethyl]-
  • BAY 294
  • 2244904-69-4