NeuN (E4M5P) Mouse mAb

Source Reactivity Background References

Product Name: NeuN (E4M5P) Mouse mAb
Chemical Name: NeuN (E4M5P) Mouse mAb
Synonyms: NeuN (E4M5P) Mouse mAb
CBNumber: CB26261946
Formula Weight: 0
MOL File: Mol file

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Hazard and Precautionary Statements (GHS)

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NeuN (E4M5P) Mouse mAb Chemical Properties,Usage,Production

Source

Mouse

Reactivity

Human;Mouse;Rat

Background

Neuronal nuclei is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, or dentate nucleus neurons. This neuronal protein was originally identified by immunoreactivity with a monoclonal antibody also called NeuN. Using MS analysis, NeuN was later identified as the Fox-3 gene product. Fox-3 contains an RNA recognition motif and functions as a splicing regulator. Fox-3 regulates alternative splicing of NumB, promoting neuronal differentiation during development.

References

[1] Mullen, R.J. et al. (1992) Development 116, 201-11.
[2] Kim, K.K. et al. (2009) J Biol Chem 284, 31052-61.
[3] Kim, K.K. et al. (2013) J Cell Biol 200, 443-58.

NeuN (E4M5P) Mouse mAb Preparation Products And Raw materials

Raw materials

Preparation Products

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NeuN (E4M5P) Mouse mAb Suppliers

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NeuN (E4M5P) Mouse mAb