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1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT

Product Name
1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT
CAS No.
1628353-02-5
Chemical Name
1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT
Synonyms
PTDINS-(3,4,5)-P3 (1,2-DIPALMITOYL) SODIUM SALT;PHOSPHATIDYLINOSITOL-3,4,5-TRIPHOSPHATE C-16 SODIUM SALT;1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT
CBNumber
CB2675372
Molecular Formula
C41H83NaO22P4
Formula Weight
1074.98
MOL File
Mol file
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1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Property

storage temp. 
Store at -20°C
solubility 
CHCl3:CH3OH:H2O (2.5:3:1): 3.8 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
A lyophilized powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
64920
Product name
PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Purity
≥98%
Packaging
100μg
Price
$47
Updated
2024/03/01
Cayman Chemical
Product number
64920
Product name
PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Purity
≥98%
Packaging
500μg
Price
$206
Updated
2024/03/01
Cayman Chemical
Product number
64920
Product name
PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Purity
≥98%
Packaging
1mg
Price
$360
Updated
2024/03/01
Cayman Chemical
Product number
64920
Product name
PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Purity
≥98%
Packaging
5mg
Price
$1570
Updated
2024/03/01
AK Scientific
Product number
3144EL
Product name
Tetrasodium;[(1R,2S,4S,5S)-3-[[(2R)-2,3-di(hexadecanoyloxy)propoxy]-oxidophosphoryl]oxy-2,4-dihydroxy-5,6-bis[[hydroxy(oxido)phosphoryl]oxy]cyclohexyl]hydrogenphosphate
Packaging
1mg
Price
$499
Updated
2021/12/16
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1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Chemical Properties,Usage,Production

Description

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins.3,4 Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references 5 and 6.

References

1. Lapetina, E.G., Billah, M.M., and Cuatrecasas, P. The phosphatidylinositol cycle and the regulation of arachidonic acid production Nature 292,367-369(1981).
2. Majerus, P.W. Inositol phosphate biochemistry Annu. Rev. Biochem. 61,225-250(1992).
3. Tanaka, K., Imajoh-Ohmi, S., Sawada, T., et al. A target of phosphatidylinositol 3,4,5-trisphosphate with a zinc finger motif similar to that of the ADP-ribosylation-factor GTPase-activating protein and two pleckstrin homology domains Eur. J. Biochem. 245,512-519(1997).
4. Yang, X., Rudolf, M., Carew, M.A., et al. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate J. Biol. Chem. 274(27),18973-18980(1999).
5. Pike, L.J., and Casey, L. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains J. Biol. Chem. 271,26453-26456(1996).
6. Berridge, M.J. Inositol trisphosphate and calcium signalling Nature 361(6410),315-325(1993).

1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Suppliers

China 11 United States 2 Global 13
Shanghai Hongye Biotechnology Co. Ltd
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1628353-02-5, 1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALTRelated Search:


  • 1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT
  • PHOSPHATIDYLINOSITOL-3,4,5-TRIPHOSPHATE C-16 SODIUM SALT
  • PTDINS-(3,4,5)-P3 (1,2-DIPALMITOYL) SODIUM SALT
  • 1628353-02-5