(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM

Product Name: (+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM
CAS No.: 127299-93-8
Chemical Name: (+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM
Synonyms: BRL 37344A;BRL 37344 SODIUM;BRL 37344 Na Salt;BRL 37344 SODIUM SALT;BRL 37344 hydrate sodium salt;(R,R)-(+/-)-4-(2-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)propyl)phenoxyaceticacid;(+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM;(R*,R*)-(+/-)-4-[2-[(2-(3-CHLOROPHENYL)-2-HYDROXYETHYL)AMINO]PROPYL]PHENOXYACETIC ACID, SODIUM SALT;(±)-(R*,R*)-[4-[2-[[2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetic acid sodium hydrate;Acetic acid, 2-[4-[(2S)-2-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]-, sodium salt (1:1), rel-
CBNumber: CB2675428
Molecular Formula: C19H23ClNNaO4
Formula Weight: 387.84
MOL File: 127299-93-8.mol

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(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Property

storage temp.: Store at RT
solubility: H₂O: 10 mg/mL
form: powder
color: white
Water Solubility: Soluble to 100 mM in water

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B169
Product name: BRL 37344 sodium salt hydrate
Purity: solid
Packaging: 5mg
Price: $131.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: B169
Product name: BRL 37344 sodium salt hydrate
Purity: solid
Packaging: 25mg
Price: $352.1
Updated: 2025/07/31

Cayman Chemical

Product number: 18622
Product name: BRL 37344 (sodium salt)
Purity: ≥98%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 18622
Product name: BRL 37344 (sodium salt)
Purity: ≥98%
Packaging: 5mg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 18622
Product name: BRL 37344 (sodium salt)
Purity: ≥98%
Packaging: 10mg
Price: $216
Updated: 2024/03/01

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(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Chemical Properties,Usage,Production

Uses

BRL 37344 Sodium is a potent and selective b3-AR agonist.

Biological Activity

Potent and selective β 3 adrenoceptor agonist (K i values are 287, 1750 and 1120 nM for β 3 , β 1 and β 2 receptors respectively). Also available as part of the β -Adrenoceptor Agonist Tocriset™ .

Biochem/physiol Actions

BRL 37344 is a selective β3-adrenoceptor agonist. Studies support the hypothesis that there are peripheral β3 adrenergic receptors that can reduce food intake and that central β2 or β3 adrenergic receptors mediate the peripheral effects of the β3 agonist.

storage

Store at RT

References

[1]. simard pm, atgié c, mauriège p, et al. comparison of the lipolytic effects of norepinephrine and brl 37344 in rat brown and white adipocytes. obes res, 1994, 2(5): 424-431.
[2]. kozlovski vi, chlopicki s, gryglewski rj. effects of two beta3-agonists, cgp 12177a and brl 37344, on coronary flow and contractility in isolated guinea pig heart. j cardiovasc pharmacol, 2003, 41(5): 706-713.
[3]. reverte m, rivas-cabañero l. effects of the beta 3-adrenoceptor agonist brl 37344 on lipomobilization and plasma glucose levels in conscious fasted rabbits. can j physiol pharmacol, 1996, 74(3): 251-256.
[4]. kasahara h, muto s, motokawa y, et al. β3-adrenoceptor-mediated increased circulating transaminase levels in mice treated with its agonist brl 37344. j toxicol sci, 2010, 35(5): 779-784.

(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Preparation Products And Raw materials

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Preparation Products

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(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Suppliers

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127299-93-8, (+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUMRelated Search:

Phenoxyacetic acid Phenoxyacetic acid sodium salt 5-[(2R)-2-([(2R)-2-(3-CHLOROPHENYL)-2-HYDROXYETHYL]AMINO)PROPYL]-1,3-BENZODIOXOLE-2,2-DICARBOXYLATE DISODIUM (+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM

(+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM

(R*,R*)-(+/-)-4-[2-[(2-(3-CHLOROPHENYL)-2-HYDROXYETHYL)AMINO]PROPYL]PHENOXYACETIC ACID, SODIUM SALT

(±)-(R*,R*)-[4-[2-[[2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetic acid sodium hydrate

BRL 37344 Na Salt

BRL 37344A

BRL 37344 SODIUM

BRL 37344 SODIUM SALT

(R,R)-(+/-)-4-(2-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)propyl)phenoxyaceticacid

BRL 37344 hydrate sodium salt

BRL 37344A, (±)-(R*,R*)-[4-[2-[[2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetic acid sodium hydrate

Acetic acid, 2-[4-[(2S)-2-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]-, sodium salt (1:1), rel-

127299-93-8

C19H21NO4ClNa

C19H21ClNNaO4

C19H21ClNNaO4xH2O

Adrenoceptor

(+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM

(+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Property

Safety

Hazard and Precautionary Statements (GHS)

N-Bromosuccinimide Price

(+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Chemical Properties,Usage,Production

Uses

Biological Activity

Biochem/physiol Actions

storage

References

(+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Suppliers

127299-93-8, (+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUMRelated Search:

(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM

(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Property

(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Chemical Properties,Usage,Production

(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Preparation Products And Raw materials

(+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM Suppliers

127299-93-8, (+/-)-(R,R)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUMRelated Search: