ChemicalBook > CAS DataBase List > NICLOFOLAN

NICLOFOLAN

Product Name
NICLOFOLAN
CAS No.
10331-57-4
Chemical Name
NICLOFOLAN
Synonyms
4-chloro-2-(5-chloro-2-hydroxy-3-nitrophenyl)-6-nitrophenol;ME 3625;Nicloflan;Bilevon M;Niclofoian;NICLOFOLAN;Bayer-9015;menichlopholan;Nicloflan Tablets;NICLOFOLAN USP/EP/BP
CBNumber
CB2677886
Molecular Formula
C12H6Cl2N2O6
Formula Weight
345.09
MOL File
10331-57-4.mol
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NICLOFOLAN Property

Boiling point:
251.5°C (rough estimate)
Density 
1.8594 (rough estimate)
refractive index 
1.7350 (estimate)
pka
4.34±0.40(Predicted)
form 
Solid
color 
Light yellow to yellow
EPA Substance Registry System
Niclofolan (10331-57-4)
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Safety

Toxicity
bird - wild,LD50,oral,13mg/kg (13mg/kg),Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0012054
Product name
NICLOFOLAN
Purity
95.00%
Packaging
5MG
Price
$499.2
Updated
2021/12/16
AK Scientific
Product number
J90160
Product name
5,5'-Dichloro-3,3'-dinitro-2,2'-biphenyldiol
Packaging
5g
Price
$995
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012054
Product name
NICLOFOLAN
Purity
95.00%
Packaging
1G
Price
$2355.15
Updated
2021/12/16
Chemenu
Product number
CM276441
Product name
5,5''-Dichloro-3,3''-dinitro-[1,1''-biphenyl]-2,2''-diol
Purity
95%
Packaging
1g
Price
$1117
Updated
2021/12/16
Crysdot
Product number
CD12185299
Product name
5,5'-Dichloro-3,3'-dinitro-[1,1'-biphenyl]-2,2'-diol
Purity
95+%
Packaging
1g
Price
$1186
Updated
2021/12/16
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NICLOFOLAN Chemical Properties,Usage,Production

Chemical Properties

Orange-yellow crystalline powder. Melting point 178-182 ℃. Soluble in acetone, glacial acetic acid and sodium hydroxide solution, slightly soluble in water and ethanol.

Uses

Niclofolan can be used as deworming drug and anti-creep drug. It is used for prevention and treatment of hepatic chioniasis of cattle and sheep.

Definition

ChEBI: Niclofolan is a polychlorobiphenyl.

Synthesis

Niclofolan is obtained by nitration of 5,5 '-dichloro-2, 2' dihydroxybiphenyl. The nitration was carried out in acetic acid at a temperature not exceeding 20℃. Then activated carbon was added for reflux decolorization for 1h. The filter was pumped with a nitrate filter rod. The filtrate was cooled below 15℃ and crystallized. Dinitrochlorophenol was obtained by filtration, washing with acetic acid and drying. The yield is 60%.

NICLOFOLAN Preparation Products And Raw materials

Raw materials

Dibenzofuran 1,3-Bisbenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid Thionyl chloride

Preparation Products

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View Lastest Price from NICLOFOLAN manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Niclofolan 10331-57-4
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-14
Dideu Industries Group Limited
Product
NICLOFOLAN 10331-57-4
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-18
Shaanxi Dideu Medichem Co. Ltd
Product
Niclofolan 10331-57-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%+
Supply Ability
800 tons
Release date
2020-04-28

10331-57-4, NICLOFOLANRelated Search:

Ferric nitrate nonahydrate Erbium(III) nitrate pentahydrate Cobaltous nitrate hexahydrate Nitrazine Yellow Ceric ammonium nitrate Isosorbide dinitrate Sodium nitroprusside dihydrate Lanthanum(III) nitrate hexahydrate THORIUM NITRATE HYDRATE ZIRCONIUM DINITRATE OXIDE Nitroclofene CERIUM(III) NITRATE HEXAHYDRATE Ferric nitrate LANTHANUM NITRATE Lithium nitrate MERCUROUS NITRATE NICLOFOLAN 5-chloro[1,1'-biphenyl]-2-ol

  • NICLOFOLAN
  • Niclofoian
  • 1'-biphenyl)-2,2'-diol, 5,5'-dichloro-3,3'-dinitro-(
  • 3,3'-dichloro-5,5'-dinitro-o,o'-biphenol
  • 4,4'-dichloro-6,6'-dinitro-o,o'-biphenol
  • 5,5'-dichloro-2,2'-dihydroxy-3,3'-dinitrobiphenyl
  • 5,5'-dichloro-3,3'-dinitro(1,1'-biphenyl)-2,2'-diol
  • menichlopholan
  • 5,5'-Dichloro-3,3'-dinitrobiphenyl-2,2'-diol
  • Bayer-9015
  • Nicloflan
  • 5,5\'-Dichloro-2,2\'-dihydroxy-3,3\'-dinitrobiphen
  • Bilevon M
  • ME 3625
  • [1,1'-Biphenyl]-2,2'-diol,5,5'-dichloro-3,3'-dinitro-
  • Nicloflan Tablets
  • 4-chloro-2-(5-chloro-2-hydroxy-3-nitrophenyl)-6-nitrophenol
  • NICLOFOLAN USP/EP/BP
  • Nitrate chlorophenol
  • 10331-57-4
  • 0331-57-4
  • C12H6Cl2N2O6
  • API