ChemicalBook > CAS DataBase List > 2,4-DIMETHYL-5-NITROANILINE

2,4-DIMETHYL-5-NITROANILINE

Product Name
2,4-DIMETHYL-5-NITROANILINE
CAS No.
2124-47-2
Chemical Name
2,4-DIMETHYL-5-NITROANILINE
Synonyms
5-Nitro-2,4-xylidine;2,4-Dimethyl-5-nitro-anilin;2,4-DIMETHYL-5-NITROANILINE;5-nitro-2,4-dimethylaniline;(2,4-dimethyl-5-nitrophenyl)am;2,4-dimethyl-5-nitrobenzenamine;5-Amino-2,4-dimethylnitrobenzene;(2,4-dimethyl-5-nitrophenyl)amine;Benzenamine, 2,4-dimethyl-5-nitro-;4-Amino-1,3-dimethyl-6-nitrobenzene
CBNumber
CB2681483
Molecular Formula
C8H10N2O2
Formula Weight
166.18
MOL File
2124-47-2.mol
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2,4-DIMETHYL-5-NITROANILINE Property

Melting point:
122.0 to 126.0 °C
Boiling point:
329.4±37.0 °C(Predicted)
Density 
1.220±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
powder to crystal
pka
2.83±0.10(Predicted)
color 
Light yellow to Brown
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2921420090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S740365
Product name
2,4-DIMETHYL-5-NITROANILINE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$30.7
Updated
2025/07/31
Sigma-Aldrich
Product number
S740365
Product name
2,4-DIMETHYL-5-NITROANILINE
Purity
Aldrich
Packaging
50mg
Price
$29.8
Updated
2024/03/01
TCI Chemical
Product number
D5196
Product name
2,4-Dimethyl-5-nitroaniline
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$68
Updated
2025/07/31
TCI Chemical
Product number
D5196
Product name
2,4-Dimethyl-5-nitroaniline
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$201
Updated
2025/07/31
Biosynth Carbosynth
Product number
FD122379
Product name
(2,4-Dimethyl-5-nitrophenyl)amine
Packaging
25g
Price
$500
Updated
2021/12/16
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2,4-DIMETHYL-5-NITROANILINE Chemical Properties,Usage,Production

Uses

2,4-Dimethyl-5-nitroaniline is a reagent that is used in the synthesis of symmetric dinitro/tetranitro-functionalized Troger''s bases via heterocyclization of nitroanilines/dinitroanilines with diglycolic acid or paraformaldehyde.

Synthesis

95-68-1

2124-47-2

The general procedure for the synthesis of 2,4-dimethyl-5-nitroaniline from 2,4-dimethylaniline is as follows: nitric acid (33 g) was added slowly and dropwise to a stirring solution of 2,4-dimethylaniline (40 g, 0.33 mmol) in concentrated hydrochloric acid over a period of 3 h, keeping the reaction temperature below 15 °C. The reaction temperature was kept below 15 °C for the first time. Subsequently, sulfuric acid (400 g) was added. After addition, the reaction mixture was continued to be stirred at 15 °C for 1 h. The reaction was then poured into ice (600 mL), stirred for 30 min and filtered. The resulting yellow filter cake was neutralized with saturated aqueous sodium bicarbonate (500 mL) and subsequently extracted with ethyl acetate (3 x 200 mL). The organic extracts were combined, dried with magnesium sulfate, filtered and the solvent was removed in vacuum to give the crude product. The crude product was recrystallized by ethanol-water mixed solvent to give a final orange solid product (39 g, 71% yield, containing 20% dinitro by-product). The product was analyzed by IR showing characteristic absorption peaks (Nujol, cm-1): 3469, 3386, 3239, 2956, 2925, 2855, 1719, 1636, 1514, 1461, 1377, 1339, 1297, 1273, 1222, 1170, 1034, 992, 885, 870, 849. 805, 758, 745, 723, 640, 607 and 571; 1H NMR (400 MHz, CDCl3) δ: 7.15 (1H, s), 6.87 (1H, s), 4.99 (2H, br.s), 2.21 (3H, s), 1.97 (3H, s).

References

[1] European Journal of Organic Chemistry, 2009, # 5, p. 687 - 698
[2] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 3, p. 403 - 427
[3] Patent: EP1147110, 2003, B1
[4] Chemische Berichte, 1884, vol. 17, p. 265
[5] Journal of the Chemical Society, 1921, vol. 119, p. 718

2,4-DIMETHYL-5-NITROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DIMETHYL-5-NITROANILINE Suppliers

Americas 1 China 110 Europe 1 France 1 Germany 2 India 7 Japan 1 United Kingdom 5 United States 13 Global 141
Interchim SA
Tel
--
Fax
--
Email
him@interchim.com
Country
France
ProdList
2725
Advantage
58
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View Lastest Price from 2,4-DIMETHYL-5-NITROANILINE manufacturers

Henan Fengda Chemical Co., Ltd
Product
2,4-DIMETHYL-5-NITROANILINE 2124-47-2
Price
US $101.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-28
Honest Joy Holdings Limited
Product
2,4-Dimethyl-5-nitro-anilin 2124-47-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99.2%
Supply Ability
100 tons
Release date
2022-01-14
Shaanxi Dideu Medichem Co. Ltd
Product
2,4-Dimethyl-5-nitroaniline 2124-47-2
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
100 tons
Release date
2020-01-10

2124-47-2, 2,4-DIMETHYL-5-NITROANILINERelated Search:

3-Amino-4,6-dimethylpyridine OXAMNIQUINE(200MG)DISCONTINUED Musk ketone 4,5-DIMETHYL-2-NITROANILINE,4,5-DIMETHYL-2-NITROANILINE / 6-NITRO-3,4-XYLIDINE 4-AMINO-NN-DIMETHYL-3-NITROANILINE 97%,4-Amino-N,N-dimethyl-3-nitroaniline, GC 97%,4-AMINO-N,N-DIMETHYL-3-NITROANILINE 3-TRIFLUOROMETHYL-N,N-DIMETHYL-4-NITROANILINE 2-TRIFLUOROMETHYL-N,N-DIMETHYL-4-NITROANILINE N,N-DIMETHYL-3-NITROANILINE,N,N-DIMETHYL-M-NITROANILINE 2,5-DIMETHYL-4-NITROANILINE 4-BROMO-2,3-DIMETHYL-6-NITROANILINE 3-AMINO-N,N-DIMETHYL-4-NITROANILINE,3-AMINO-NN-DIMETHYL-4-NITROANILINE 97% 4,6-DIMETHYL-2-NITROANILINE,4,6-DIMETHYL-2-NITROANILINE, TECH., 90% 4-Fluoro-N,N-dimethyl-2-nitroaniline N,2-DIMETHYL-4-NITROANILINE N,N-DIMETHYL-O-NITROANILINE,N,N-DIMETHYL-2-NITROANILINE N,N-Dimethyl-4-nitroaniline, 98+%,N,N-DIMETHYL-P-NITROANILINE,N,N-DIMETHYL-4-NITROANILINE 2,3-DIMETHYL-6-NITROANILINE,2,3-DIMETHYL-6-NITROANILINE 98% 2-CHLORO-N,N-DIMETHYL-4-NITROANILINE

  • 2,4-<WBR>DIMETHYL-<WBR>5-<WBR>NITROANILINE
  • 2,4-Dimethyl-5-nitro-anilin
  • 2,4-dimethyl-5-nitrobenzenamine
  • 5-Amino-2,4-dimethylnitrobenzene
  • 5-Nitro-2,4-xylidine
  • (2,4-dimethyl-5-nitrophenyl)amine
  • 2,4-DIMETHYL-5-NITROANILINE
  • 4-Amino-1,3-dimethyl-6-nitrobenzene
  • 5-Amino-2,4-dimethylnitrobenzene, 5-Nitro-2,4-xylidine
  • Benzenamine, 2,4-dimethyl-5-nitro-
  • 2,4-Dimethyl-5-Nitroaniline(WXC01839)
  • 5-nitro-2,4-dimethylaniline
  • (2,4-dimethyl-5-nitrophenyl)am
  • 2,4-DIMETHYL-5-NITROANILINE ISO 9001：2015 REACH
  • 2124-47-2