9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE
- Product Name
- 9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE
- CAS No.
- 70173-54-5
- Chemical Name
- 9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE
- Synonyms
- 9-Bromo-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline;4-BROMO-JULOLIDINE;9-BROMO-JULOLIDINE;1H,5H-Benzo[ij]quinolizine, 9-bromo-2,3,6,7-tetrahydro-;9-Bromo-2,3,6,7-tetrahydro-1h,5h-pyrido[3,2,1-ij]quinolone;9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE
- CBNumber
- CB2682268
- Molecular Formula
- C12H14BrN
- Formula Weight
- 252.15
- MOL File
- 70173-54-5.mol
9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE Property
- Melting point:
- 36.5 °C
- Boiling point:
- 135.0-136.5 °C(Press: 0.15 Torr)
- Density
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 5.61±0.20(Predicted)
- Appearance
- Brown to reddish brown <36.5°C Solid,>36.5°C Liquid
- CAS DataBase Reference
- 70173-54-5(CAS DataBase Reference)
Safety
- Risk Statements
- 20/21/22
- Safety Statements
- 22-36/37/39
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B678488
- Product name
- 9-Bromo-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-IJ]quinoline
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 0873AC
- Product name
- 9-Bromo-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline
- Packaging
- 1g
- Price
- $197
- Updated
- 2021/12/16
- Product number
- HCH0025465
- Product name
- 9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $425
- Updated
- 2021/12/16
- Product number
- HCH0025465
- Product name
- 9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $650
- Updated
- 2021/12/16
- Product number
- CD11069939
- Product name
- 9-Bromo-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline
- Purity
- 95+%
- Packaging
- 25g
- Price
- $891
- Updated
- 2021/12/16
9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE Chemical Properties,Usage,Production
Chemical Properties
White Crystalline
Synthesis
479-59-4
70173-54-5
The general procedure for the synthesis of 9-bromo-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline from julolidine: julolidine (675 mg, 3.90 mmol) and N-bromosuccinimide (832 mg, 4.68 mmol) were dissolved in 10 mL of N,N-dimethylformamide (DMF), and the reaction was stirred at room temperature for 5 hours. After completion of the reaction, the crude product was purified by silica gel column chromatography (eluent: hexane/dichloromethane, 3:1, v/v) to afford the target compound 9-bromo-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline (786 mg, 80% yield) as an oil. The structure of the product was confirmed by the following characterization: 1H NMR (500 MHz, CDCl3) δ/ppm: 6.87 (s, 2H), 3.10 (t, 4H, J=5.50 Hz), 2.70 (t, 4H, J=6.35 Hz), 1.94 (m, 4H); 13C NMR (500 MHz, CDCl3) δ/ppm: 142.0 ,129.3,123.7,107.3,50.0,27.6,21.9; IR (KBr, cm-1): 3045,2935,2836,1581,1506,1462,1446,1310; high-resolution mass spectrometry (TOFMS-EI) m/z: calculated value C12H14NBr [M]+ 251.0310 , measured value 251.0309.
References
[1] Chemical and Pharmaceutical Bulletin, 1984, vol. 32, # 5, p. 1770 - 1779
[2] Canadian Journal of Chemistry, 2009, vol. 87, # 2, p. 440 - 447
[3] Journal of Organic Chemistry, 2011, vol. 76, # 22, p. 9391 - 9408
[4] Dyes and Pigments, 2013, vol. 99, # 3, p. 653 - 660
[5] European Journal of Organic Chemistry, 2011, # 30, p. 6100 - 6109
9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE Suppliers
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