Enoximone

Product Name: Enoximone
CAS No.: 77671-31-9
Chemical Name: Enoximone
Synonyms: Perfan;Pedane;RMI-17043;ENOXIMONE;MDL-17043;Fenoximone;Enoximone USP/EP/BP;4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one;1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE;4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one
CBNumber: CB2682723
Molecular Formula: C12H12N2O2S
Formula Weight: 248.3
MOL File: 77671-31-9.mol

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Enoximone Property

Melting point:: 255-258°C
Density: 1.33
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO: 28 mg/mL, soluble
pka: 10.37±0.70(Predicted)
form: solid
color: light yellow
CAS DataBase Reference: 77671-31-9(CAS DataBase Reference)

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Safety

RIDADR: 3249
WGK Germany: 3
HazardClass: 6.1(b)
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E1279
Product name: Enoximone
Purity: solid
Packaging: 10mg
Price: $270
Updated: 2024/03/01

Sigma-Aldrich

Product number: E1279
Product name: Enoximone
Purity: solid
Packaging: 50mg
Price: $905
Updated: 2022/05/15

Tocris

Product number: 1693
Product name: Enoximone
Purity: ≥99%(HPLC)
Packaging: 10
Price: $169
Updated: 2021/12/16

Tocris

Product number: 1693
Product name: Enoximone
Purity: ≥99%(HPLC)
Packaging: 50
Price: $711
Updated: 2021/12/16

Usbiological

Product number: 255248
Product name: Enoximone
Packaging: 10mg
Price: $423
Updated: 2021/12/16

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Enoximone Chemical Properties,Usage,Production

Description

Enoximone is a phosphodiesterase inhibitor indicated for selective use as a cardiostimulant in heart transplant patient maintenance. It is currently being investigated for other indications including acute congestive heart failure.

Originator

Merrell Dow (USA)

Uses

Enoximone is a phosphodiesterase inhibitor used in the treatment of congestive heart failure and is selective to phosphodiesterase 3. Potent PDE-3 inhibitor.

Definition

ChEBI: Enoximone is an aromatic ketone.

brand name

Perfan IV

Biological Activity

Inhibitor of type III phosphodiesterase (PDE3). Increases intracellular cyclic AMP (cAMP) concentrations and enhances myocardial contractility. Also induces concentration-dependent vasodilation in vitro .

Biochem/physiol Actions

Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart.

storage

Store at +4°C

Enoximone Preparation Products And Raw materials

Raw materials

NITROUS ACID Ethyl acetate

Preparation Products

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Enoximone Suppliers

China 59 Europe 4 Japan 1 Switzerland 1 United Kingdom 7 United States 24 USA 1 Global 97

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9809
Advantage: 59

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

Jinan Mingya Medical Technology Co., Ltd.

Tel: 0531-85828981
Fax: +86-531-85806006
Email: 864598798@qq.com
Country: China
ProdList: 588
Advantage: 58

3B Scientific (Wuhan) Corporation Limited

Tel: 0086-27-88063677 18186135292
Fax: 027-88063656
Email: sales@3bsc.com
Country: China
ProdList: 292
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6463
Advantage: 55

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View Lastest Price from Enoximone manufacturers

Career Henan Chemica Co

Product: Enoximone 77671-31-9
Price: US $1.00/g
Min. Order: 1g
Purity: 85.0-99.8%
Supply Ability: 20tons
Release date: 2020-10-28

77671-31-9, EnoximoneRelated Search:

Methyl salicylate Imidazole Hexamethylphosphoramide Dihydromyrcenol 1-Methylimidazole Basic Violet 1 Phenylmethylsulfonyl fluoride Tribenuron methyl Methylparaben Methyl acrylate Methanol Kresoxim-methyl 1-(2,6-Dimethylphenoxy)-2-propanamine Methyl 4-Ethyl-1,3-dihydro-imidazol-2-one 4,5-DIMETHYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE 4-ACETYL-5-METHYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE enoximone sulfoxide

ENOXIMONE

2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)-

Fenoximone

MDL-17043

Pedane

Perfan

RMI-17043

4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one

1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE

4-Methyl-5-[4-(methylthio)benzoyl]-1,3-dihydro-2H-imidazol-2-one

Enoximone USP/EP/BP

4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one

inhibit,Enoximone,bronchodilatory,CD11b,eosinophils,vasodilating,Phosphodiesterase (PDE),airway,cAMP,PDE3,PDE4A,Inhibitor,anti-inflammatory,Antiasthma

77671-31-9

BioChemical

Cell Signaling and Neuroscience

G Proteins and Cyclic Nucleotides

Phosphodiesterase Inhibitors

Cyclic Nucleotide Metabolism

Cell Biology

APIs

API