5-Chloropentanol
- Product Name
- 5-Chloropentanol
- CAS No.
- 5259-98-3
- Chemical Name
- 5-Chloropentanol
- Synonyms
- 5-Chloro;Chloropentanol;oro-1-pentanoL;5-CHLOROPENTANOL;5-chloro-1-pentano;1-CHLORO-5-PENTANOL;5-CHLORO-1-PENTANOL;5-Chloropentan-1-ol;5-CHLOROPENTANE-1-OL;Apixaban Impurity 75
- CBNumber
- CB2688543
- Molecular Formula
- C5H11ClO
- Formula Weight
- 122.59
- MOL File
- 5259-98-3.mol
5-Chloropentanol Property
- Boiling point:
- 107 °C
- Density
- 1,06 g/cm3
- refractive index
- 1.454
- Flash point:
- 102-103°C/8mm
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO, Methanol (Sparingly)
- form
- Oil
- pka
- 15.12±0.10(Predicted)
- Specific Gravity
- 1.06
- color
- Clear Colourless
- Water Solubility
- Slightly soluble in water.
- BRN
- 1732314
- InChIKey
- DCBJCKDOZLTTDW-UHFFFAOYSA-N
- CAS DataBase Reference
- 5259-98-3(CAS DataBase Reference)
- EPA Substance Registry System
- 1-Pentanol, 5-chloro- (5259-98-3)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 22-36/38
- Safety Statements
- 26-36/37/39
- Hazard Note
- Irritant/Harmful
- TSCA
- Yes
- PackingGroup
- III
- HS Code
- 2905190098
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C0815
- Product name
- 5-Chloro-1-pentanol
- Purity
- >90.0%(GC)
- Packaging
- 5mL
- Price
- $49
- Updated
- 2025/07/31
- Product number
- C0815
- Product name
- 5-Chloro-1-pentanol
- Purity
- >90.0%(GC)
- Packaging
- 25mL
- Price
- $139
- Updated
- 2025/07/31
- Product number
- C350340
- Product name
- 5-Chloro-1-pentanol
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 008844
- Product name
- 5-Chloro-1-pentanol
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- 008844
- Product name
- 5-Chloro-1-pentanol
- Packaging
- 5g
- Price
- $14
- Updated
- 2021/12/16
5-Chloropentanol Chemical Properties,Usage,Production
Uses
5-Chloro-1-pentanol is used to produce 6-hydroxy-hexanenitrile at temperature of 90 - 100°C. It is also is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Synthesis
20395-28-2
5259-98-3
The general procedure for the synthesis of 5-chloro-1-pentanol from 5-chloropentyl acetate was as follows: 5-chloropentanol-1-acetate (33.9 g, 0.21 mol) was mixed with 95% ethanol (75 mL) and 2N aqueous NaOH (90 mL) according to the method reported by Meyers et al. (Tetrahedron 27, 5979-85), and shaken to homogeneous. The mixed solution was allowed to stand at room temperature for a few hours and the ethanol was subsequently removed by distillation under reduced pressure. The residue was extracted with ether (3 x 150 mL). The extract was dried over anhydrous potassium carbonate, the solvent was removed under reduced pressure and finally 5-chloro-1-pentanol was obtained by distillation as a colorless oil (21.1 g, 84% yield, literature value 72%) with a boiling point of 35-37°C (0.02 mmHg) (literature value 62°C (0.5 mmHg)). The product was characterized by the following data: IR (thin film) cm-1 3330 (broad peak), 2945, 2875, 1455, 1440, 1315, 1295, 1265, 1150, 1075, 1060, 1020, 1000, 965, 900, 740, 725, 655; 1H NMR (200 MHz, CDCl3) δ 3.67 (m, 2H), 3.55 (t, J=6.5 Hz, 2H), 1.82 (pentet, J=7 Hz, 2H), 1.4-1.7 (m, 4H), 1.37 (m, 1H); 13C NMR (22.5 MHz, CDCl3) δ 62.4, 45.0, 32.4, 31.9, 23.2; Mass Spectra (70 eV) m/z (relative abundance) 124, 122 (M+, not observed), 106, 104 (M+ - H2O, 0.7, 1.3), 105 (0.5), 93 (7.1), 91 (20.5), 69 (13.7), 68 (100.0), 67 (13.6), 57 (13.4), 56 (41.4), 55 ( 57.0).
References
[1] Journal of the American Chemical Society, 1983, vol. 105, # 12, p. 4008 - 4017
[2] Synthetic Communications, 1985, vol. 15, # 7, p. 569 - 580
[3] Patent: US5264619, 1993, A
[4] Journal of Organic Chemistry, 1981, vol. 46, # 16, p. 3361 - 3364
[5] Phosphorus and Sulfur and the Related Elements, 1987, vol. 31, p. 161 - 176
5-Chloropentanol Preparation Products And Raw materials
Raw materials
Preparation Products
5-Chloropentanol Suppliers
- Tel
- 021-69106960 13701823733
- Fax
- 021-69106780
- 13701823733@163.com
- Country
- China
- ProdList
- 4641
- Advantage
- 60
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 010-60275820 13031183356
- Fax
- 010-60270825
- elainezt@sina.com
- Country
- China
- ProdList
- 1390
- Advantage
- 62
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
View Lastest Price from 5-Chloropentanol manufacturers
- Product
- 5-Chloropentanol 5259-98-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-04-12
- Product
- Apixaban Impurity 75
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 98%
- Supply Ability
- 500mg
- Release date
- 2024-06-05
- Product
- 5-Chloropentanol 5259-98-3
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2020-01-10