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(±)-Cloprostenol sodium salt

Product Name
(±)-Cloprostenol sodium salt
CAS No.
55028-72-3
Chemical Name
(±)-Cloprostenol sodium salt
Synonyms
CLOPROSTENOL SODIUM;D-Cloprostenol sodiuM;DL-Cloprostenol sodiuM;16-(3-CHLOROPHENOXY)-9,11,15R-TRIHYDROXY-17,18,19,20-TETRANORPROSTA-5Z,13E-DIEN-1-OIC ACID SODIUM SALT;sodium(Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate;Ciosin;Planate;Estrumat;CLOPROSTENOL NA;15(S)-CLOPROSTENOL
CBNumber
CB7699245
Molecular Formula
C22H30ClNaO6
Formula Weight
448.92
MOL File
55028-72-3.mol
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(±)-Cloprostenol sodium salt Property

Melting point:
68-70 °C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
H2O: >10 mg/mL
form 
solid
color 
light brown
Water Solubility 
H2O: >10mg/mL
InChIKey
IFEJLMHZNQJGQU-KXXGZHCCSA-M
CAS DataBase Reference
55028-72-3(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
60-22-36/37/38
Safety Statements 
53-26-36/37/39-45
WGK Germany 
3
HS Code 
2937500000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C6116
Product name
(+/-)-Cloprostenol sodium salt hydrate
Purity
≥98% (HPLC), powder
Packaging
1mg
Price
$93.3
Updated
2024/03/01
Sigma-Aldrich
Product number
C6116
Product name
(+/-)-Cloprostenol sodium salt hydrate
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$372
Updated
2024/03/01
Sigma-Aldrich
Product number
1140666
Product name
Cloprostenol sodium
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
400mg
Price
$3790
Updated
2024/03/01
Sigma-Aldrich
Product number
BP628
Product name
Cloprostenol sodium
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
50MG
Price
$263
Updated
2023/06/20
Cayman Chemical
Product number
16764
Product name
Cloprostenol (sodium salt)
Purity
≥98%
Packaging
1mg
Price
$57
Updated
2024/03/01
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(±)-Cloprostenol sodium salt Chemical Properties,Usage,Production

Description

±)-Cloprostenol sodium salt is the d-enantiomer of Cloprostenol (C587300), an aryl-oxymethyl analog of prostaglandin F2α.

Uses

(±)-Cloprostenol sodium salt is a prostaglandin that dissolves the corpus luteum of cattle and is used as a veterinary drug.

brand name

Estrumate(Bayer Animal Health).

General Description

Cloprostenol sodium (Estrumate)is available as the sodium salt from Bayer AgriculturalDivision or Bayvet Division of Miles Laboratory as an aqueoussolution containing 250 mg/mL.

Biological Activity

Water-soluble prostaglandin F 2 α (PGF 2 α ) analog; acts as a potent FP receptor agonist (EC 50 = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo .

Side effects

A low incidence of clostridial and other infections at the injection site has been reported following prostaglandin administration. Treated animals should be closely observed post injection and appropriate antibiotic therapy initiated at the first sign(s) of infection.
Very rarely, anaphylactic reactions have occurred after administration of the product. Overdose: At 50 and 100 times the recommended dose of cloprostenol mild side effects may be detected. These include increased uneasiness, mild transient diarrhea, slight frothing, and milk letdown.

Veterinary Drugs and Treatments

Cloprostenol is approved for use in beef or dairy cattle to induce luteolysis. It is recommended by the manufacturer for unobserved or undetected estrus in cows cycling normally, pyometra or chronic endometritis, expulsion of mummified fetus, luteal cysts, induced abortions after mismating, and to schedule estrus and ovulation for controlled breeding.
Cloprostenol has been used in dogs for pregnancy termination and treatment of open pyometra. The use of cloprostenol for pyometra is controversial as some believe dinoprost (PGF2alpha) is more effective and has fewer adverse effects than cloprostenol.

Solubility in water

Soluble in H2O.

(±)-Cloprostenol sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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(±)-Cloprostenol sodium salt Suppliers

Canada 1 China 192 China Hong Kong 1 Europe 2 France 1 Germany 2 India 10 Japan 1 South Korea 1 Switzerland 3 United Kingdom 4 United States 23 Global 241
Taizhou KEDE Chemical Co., Ltd
Tel
0576-84613060 13093829633
Fax
0576-84613060
Email
sales@kedechemical.com
Country
China
ProdList
298
Advantage
60
Huigen Biotech (Shanghai) Co., Ltd.
Tel
13761582449; 13761582449
Email
qingqing_claire@126.com
Country
China
ProdList
189
Advantage
58
Taizhou Crene Biotechnology Co. Ltd.
Tel
+86-0576-88813233 +86-13396860566
Email
sales@pharm-intermediates.com
Country
China
ProdList
1991
Advantage
58
Jinan Junnuo Trading Co., LTD
Tel
13345898948
Email
1301260554@qq.com
Country
China
ProdList
127
Advantage
58
Hubei Hongfuda Biotechnology Co., Ltd.
Tel
191-07255884 19107255884
Email
259506217@qq.com
Country
China
ProdList
1755
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
Email
info@chemvon.com
Country
China
ProdList
371
Advantage
57
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
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View Lastest Price from (±)-Cloprostenol sodium salt manufacturers

Sinoway Industrial co., ltd.
Product
DL-Cloprostenol Sodium 55028-72-3
Price
US $0.00/KG
Min. Order
2KG
Purity
98% up, GMP, DMF
Supply Ability
20 tons
Release date
2022-08-24
WUHAN FORTUNA CHEMICAL CO., LTD
Product
(±)-Cloprostenol sodium salt 55028-72-3
Price
US $1.00/g
Min. Order
1g
Purity
97%~102.5%,USP42
Supply Ability
5kg/month
Release date
2021-06-10
Wuhan Senwayer Century Chemical Co.,Ltd
Product
(±)-Cloprostenol sodium salt 55028-72-3
Price
US $15.00/gram
Min. Order
10gram
Purity
99%
Supply Ability
50000 kilograms
Release date
2022-11-30

55028-72-3, (±)-Cloprostenol sodium saltRelated Search:

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  • 15-EPI CLOPROSTENOL
  • 15(S)-CLOPROSTENOL
  • 16-(3-CHLOROPHENOXY)-9,11,15R-TRIHYDROXY-17,18,19,20-TETRANORPROSTA-5Z,13E-DIEN-1-OIC ACID SODIUM SALT
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  • 7-(2-[4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl)-5-heptenoic acid
  • (5Z)-rel-Cloprostenol SodiuM
  • DL-Cloprostenol sodiuM
  • (+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid hydrate sodium salt
  • (+/-)-Cloprostenol hydrate sodium salt
  • (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoicacidmonosodiumsalt
  • (+/-)-Cloprostenol sodium salt hydrate,(+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid sodium salt hydrate
  • Cloprostenol Sodium (400 mg)
  • D-Cloprostenol sodiuM
  • DL-Cloprostenol Sodium Salt
  • (+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid sodium salt hydrate
  • Cloprostenol sodium, >=99%
  • 7-[-2-[4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid sodium salt
  • sodium(Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate
  • sodium(Z)-7-(2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-
  • Sodium chlorprostaglandin
  • 16-(M-CHLOROPHENOXY)-TETRANOR-PROSTAGLANDIN-F2ALPHA, SODIUM SALT
  • (+/-)-9ALPHA,11ALPHA,15-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, SODIUM SALT
  • (+/-)-9ALPHA,11ALPHA,15S-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
  • (+)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, SODIUM SALT
  • 7-(2-[4-(3-CHLOROPHENOXY)-3-HYDROXY-1-BUTENYL]-3,5-DIHYDROXY-CYCLOPENTYL)-5-HEPTENOIC ACID SODIUM SALT
  • (5Z)-REL-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-CHLOROPHENOXY)-3-HYDROXY-1-BUTENYL]-3,5-DIHYDROXYCYCLOPENTYL]-5-HEPTENOIC ACID MONOSODIUM SALT
  • CLOPROSTENOL SODIUM
  • CLOPROSTENOL NA
  • (+)-CLOPROSTENOL SODIUM SALT
  • (+/-)-CLOPROSTENOL SODIUM SALT
  • CLOPROSTENOL SODIUM SALT
  • (+)-Cloprostenol Sodium (Subject to Patent Free)
  • sodium [1alpha(Z),2beta(1E,3R*),3alpha,5alpha]-(±)-7-[2-[4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate
  • CloprostadilSodium
  • 5-Heptenoic acid, 7-(1R,2R,3R,5S)-2-(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl-3,5-dihydroxycyclopentyl-, monosodium salt, (5Z)-rel-
  • Sodium [1alpha(Z),2beta(1E,3R*),3alpha,5alpha]-(+/-)-7-[2-[4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate
  • (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3S)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid Sodium Salt
  • Ciosin
  • Estrumat
  • Planate
  • ICI 80996 sodium salt
  • (±)-Cloprostenol sodium salt USP/EP/BP
  • Cloprostenol Sodium (1140666)
  • (+/-)-Cloprostenol sodium salt hydrate
  • Sodium (Z)-rel-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate
  • 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, sodium salt (1:1), (5Z)-rel-
  • (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-Heptenoic acid sodium salt (1:1)
  • Cloprostenol Impurity 5 (DL-Cloprostenol Sodium Salt)
  • API for veterinary drug/(±)-Cloprostenol sodium salt
  • Deferoxamine Impurity 2
  • 55028-72-3
  • 55028-50-8
  • 40665-92-7(62561-03-
  • C22H28O6ClNa
  • C22H28ClNaO6
  • C22H29ClO6
  • Other APIs
  • Pharmaceuticals